Snowstorm headed to Southeast: North Carolina, South Carolina, Georgia declare state of emergency
Ice chunks float in the Hudson River in front of the skyline of midtown Manhattan and the Empire State Building in New York City as seen from Hoboken, New Jersey, Jan. 26, 2026. (Gary Hershorn/ABC News)
(NEW YORK) — A massive snowstorm is headed to the Southeast this weekend, with blizzard conditions possible for millions.
Here’s the latest forecast:
The storm begins Friday night, bringing snow to eastern Tennessee, southern Virginia, northern South Carolina, northeastern Georgia and nearly all of North Carolina.
The brunt of the storm will hit on Saturday.
Six to 12 inches of snow is expected in Appalachia along the Tennessee-North Carolina border and in western Virginia.
Norfolk, Virginia, and other cities along the North Carolina and Virginia coast could see 7 to 12 inches of snow on Saturday and Sunday, along with wind gusts up to 70 mph.
In North Carolina, Asheville could get 5 to 7 inches of snow and Raleigh is on alert for 4 to 7 inches of snow.
Wilmington, North Carolina, could see 5 to 8 inches of snow while Charlotte could see 4 to 7 inches along with wind gusts up to 30 mph.
Further south, Charleston, South Carolina, could see get 3 to 5 inches of snow through Sunday morning, while Athens, Georgia, could see 2 to 4 inches with wind gusts up to 35 mph.
The governors of North Carolina, South Carolina and Georgia have declared state of emergencies.
“The State Emergency Response Team is activated and is positioning resources across the state to quickly respond to any needs,” North Carolina Gov. Josh Stein said on social media. “Starting Friday depending where you are, please stay off the roads if you do not have to travel.”
By Sunday morning, snow may still be falling along the coasts of North Carolina, Virginia, Delaware and Massachusetts. By Sunday afternoon, much of the snow will be over, with only Massachusetts’ Cape Cod still getting snow by the evening.
The only real appreciable snow for the Northeast will be on Cape Cod, where 1 to 3 inches is possible. The rest of the Northeast coast will see flurries and likely less than an inch of accumulation.
Pfizer logo (Photo Illustration by Nikolas Kokovlis/NurPhoto via Getty Images)
(NEW YORK) — Earlier this week, pharmaceutical company Pfizer and its partner Valneva announced that an experimental Lyme disease vaccine showed more than 70% efficacy in late-stage clinical trials.
The candidate, PF-07307405, showed 73.2% efficacy in reducing confirmed cases of Lyme disease cases after the fourth and final dose was administered when compared to a placebo.
However, the companies said there were fewer than anticipated cases of Lyme disease during the trial period and the study missed an important benchmark.
The trial did not reach its primary endpoint to provide an idea of how the results of this vaccine would turn out in a much larger population of people. Only with re-analyzing the data were researchers able to generate a statistically meaningful result.
Experts in tick-borne diseases told ABC News they still need to see the full data from the trials and that it’s early to determine what kind of impact the vaccine will have — but they add that results are “encouraging.”
“There are many other companies that are trying to develop something, but those are years and years and years away from being anywhere close to being marketed,” Dr. Gene Shapiro, a professor of pediatric infectious diseases and epidemiology of microbial diseases, told ABC News. “So, this vaccine was very similar to the vaccine that we know worked in the past. I think we have to pay attention to [this new one].”
Lyme disease is a bacterial infection that is spread through the bite of blacklegged ticks, also known as deer ticks, according to the Centers for Disease Control and Prevention (CDC).
Symptoms include fever, headache, fatigue and a skin rash known as erythema migrans, the CDC says. If left untreated, the infection can spread to joints, the heart and the nervous system.
More than 89,000 cases of Lyme disease were reported to the CDC by state health departments and the District of Columbia in 2023, according to the latest data available from the federal health agency. Estimates suggest about 476,000 Americans may be diagnosed and treated for Lyme disease annually.
Currently, no vaccine for Lyme disease is available in the U.S. Previously, a vaccine was available, but it was discontinued in 2002, according to the CDC.
“The uptake was poor. The sales were poor, and the company decided to stop selling it,” Shapiro said. “The currently developed vaccine [by Pfizer and Valneva] is very, very similar to that vaccine, with very minor modifications.”
Dr. Martin Becker, a clinical associate professor in the department of medicine at NYU Grossman Long Island School of Medicine, added that there were concerns raised, including about vaccine recipients having joint problems but several studies examining a link failed to find an association.
Becker said there have been many clinical trials underway “but this one that Pfizer just announced, I believe, is the one that’s been most advanced,” he told ABC News. “We were eagerly awaiting results from this large Phase III trial. Other previous trials were already published showing the safety and immunogenicity [of the vaccine].”
Pfizer and Valneva said they are planning to file for approval with the U.S. Food and Drug Administration, with Pfizer telling ABC News that the trial results show there is a level of protection against Lyme disease.
“It doesn’t mean it doesn’t work, but it does mean — if we had higher numbers of incidence of infection — we would be more confident about the degree of protection. It’s very encouraging,” Becker said.
Questions remain about whether the vaccine, if approved, will have higher uptake than the previous vaccine did decades earlier.
Shapiro said there might be more uptake with this vaccine if stronger recommendations are made. At the time the old vaccine was approved by federal regulators, Shapiro said the recommendation from the CDC’s Advisory Committee on Immunization Practices was to consider the shot for those at higher risk, but it was not recommended for those at low or no risk.
“It was not a very strong recommendation,” Shapiro said. “And I think there was less awareness of Lyme disease. So, most likely, [the newer vaccine] would get a stronger endorsement today.”
Virginia Governor Abigail Spanberger delivers Democratic response to the 2026 State of the Union address by President Donald Trump, Feb. 24, 2026. (ABC News)
In her roughly 12-minute speech, delivered live in front of a crowd in colonial Williamsburg, Spanberger focused on affordability and made pointed remarks about Trump’s hardline immigration policies.
“Let me ask you, the American people watching at home, three questions,” Spanberger said. “Is the president working to make life more affordable for you and your family? Is the president working to keep Americans safe both at home and abroad? Is the president working for you?”
Spanberger, who was inaugurated in January after serving three terms in the House of Representatives, hit on key issues of affordability, including lowering the persistently high costs of housing, health care, energy and groceries despite the Trump administration’s insistence that some of these costs have come down.
“Democrats across the country are laser focused on affordability in our nation’s capital and in state capitols and communities across America,” Spanberger said.
The daughter of a law enforcement officer and a nurse, Spanberger focused relentlessly on affordability throughout her 2025 gubernatorial campaign. Despite the economy being the top issue Trump ran on in the 2024 election, it’s been one of the issues he’s struggled with the most during his second term, as Americans still haven’t felt the “Trump boom” they were promised.
In an ABC News/Washington Post/Ipsos poll, 57% of Americans disapprove of how Trump’s handling the economy, and 64% disapproved of how he’s handling tariffs on imported goods.
Spanberger, a former CIA officer, also criticized the Trump for his role on the world stage, saying he is contributing to greater worldwide uncertainty, saying, “Our president has endangered the long and storied history of the United States of America, being a force for good.”
A former federal law enforcement officer who worked on narcotics and money-laundering cases for the U.S. Postal Inspection Service, Spanberger also addressed what critics call the chaos caused by the Trump administration, which continues its immigration enforcement efforts that Americans are seeing in their communities.
“Our president has sent poorly trained federal agents into our cities where they have arrested and detained American citizens and people who aspire to be Americans,” Spanberger said in her speech. She referred to mothers being taken away from their babies and children — including “a little boy in a blue bunny hat” –being sent to “far-off detention centers.”
She added: “Our broken immigration system is something to be fixed not an excuse for unaccountable agents to terrorize our communities.”
The governor gave her speech live from Colonial Williamsburg, the restored 18th century capital where Virginian representatives voted for its delegation to Congress to propose independence for all 13 colonies from Great Britain, and later adopted the Virginia Declaration of Rights — which influenced the Declaration of Independence and Bill of Rights.
“In his speech tonight, the president did what he always does,” Spanberger said. He “lied, he scapegoated, and he distracted. And he offered no real solutions to our nation’s pressing challenges, so many of which he is actively making worse.”
There were at least two major counter events that several Democrats planned to attend, including MoveOn’s People’s State of the Union, which is promoting the participation of more than 20 members of Congress; and the “State of the Swamp” event by Defiance.org that features a handful of celebrities appearing by video or in person, such as Robert De Niro.
Spanberger prepared for her remarks by watching speeches other Democrats have delivered in response to Trump’s previous addresses to Congress.
