FDA approves breakthrough drug to treat advanced pancreatic cancer
FDA sign at its headquarters in Washington, D.C. (Getty Images stock photo/JHVEPhoto)
(WASHINGTON) — The Food and Drug Administration approved on Wednesday a drug that could extend the survival of those with metastatic pancreatic cancer.
The drug, called daraxonrasib, will be sold under the brand name Rasonque. The daily pill targets multiple forms of a protein called RAS, which is a main driver of tumor growth.
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Workers wearing protective visit a patient in an isolation unit an Ebola treatment center on June 2, 2026 in Monigi, Democratic Republic of Congo. (Daniel Buuma/Getty Images)
(GENEVA) — The World Health Organization said on Thursday that the risk of Ebola transmission in Europe and World Cup host countries is low as the tournament gets ready to kick off across the U.S., Canada and Mexico.
Dr Hans Henri P. Kluge, WHO’s regional director for Europe, said in a statement that there are currently no Ebola cases in North America or Europe amid an outbreak spreading in the Democratic Republic of Congo.
The DRC has recorded 676 confirmed cases as of Thursday morning, according to DRC’s minister of health. In Uganda, there are 19 confirmed cases — many of them travel-related — and two deaths, the country’s health officials said.
Kluge made reference to an Ebola patient who was treated in the European Region after being evacuated from the outbreak region.
An American physician, Dr. Peter Stafford, tested positive for Ebola after being exposed while treating patients at Nyankunde Hospital. Stafford, a medical missionary with the mission organization Serge, was transferred to Germany and treated at Berlin’s Charite University Hospital.
His wife, Dr. Rebekah Stafford, and their four children were also transferred to the same hospital, where they were monitored in quarantine for 21 days as high-risk contacts.
Last week, the family was released from the hospital after Dr. Peter Stafford had no symptoms for more than 72 hours and a negative result in repeated PCR tests, Serge said.
“There is no reason to change your plans. Travel as normal, stay informed and enjoy the tournament,” Kluge said.
Kluge said there are several reasons why the risk is low in other countries: most cases are in remote areas of the DRC, Ebola is not an airborne illness and it is spread through direct contact with the bodily fluids of a sick person.
Additionally, screening is in place before travel is allowed from affected regions and people are only infectious once visibly ill, according to Kluge.
The CDC has temporarily restricted entry to the U.S. for certain travelers who were recently in the DRC, Uganda or South Sudan. Currently, U.S. citizens and nationals may still enter but will undergo enhanced public health screenings.
Kludge said the WHO does not recommend travel restrictions, “though if you don’t have to travel to the affected areas in the Democratic Republic of the Congo or Uganda, it is safer not to.”
He added that it’s important to challenge the stigma associated with Ebola patients and those from affected regions or African communities.
“The spread of Ebola is not determined by nationality or ethnicity,” he said. “Stigma discourages people from seeking care and can make outbreaks harder to control. Stay informed, rely on trusted sources and treat others with understanding. With common sense and compassion, we can keep both people and the game safe.”
Cyclospora cayetanensis is a unicellular parasite that causes an intestinal infection called cyclosporiasis. (CDC)
(NEW YORK) — Hospitalizations in Michigan linked to an outbreak of cyclosporiasis, an intestinal illness caused by a parasite, have surpassed 100, health officials said Friday.
So far, 102 people have been hospitalized, according to the Michigan Department of Health and Human Services (MDHHS). There are more than 5,000 cases in the state, an increase of nearly 700 since Thursday, officials said.
The Centers for Disease Control and Prevention and the Food and Drug Administration are warning consumers not to eat shredded iceberg lettuce sold at select Taco Bells in five states — Indiana, Kentucky, Michigan, Ohio, and West Virginia — after the ingredient was linked to the outbreak. The CDC said that shredded iceberg lettuce sold in grocery stores or served in other restaurants is not affected.
Lettuce supplier Taylor Farms said it is voluntarily removing all iceberg lettuce sourced from central Mexico from the U.S. market.
Taylor Farms said the FDA traceback indicated a “specific farm” that accounts for “less than 1% of the U.S.’s iceberg lettuce supply” was a potential source, and they have removed all iceberg lettuce from the region indefinitely. No other Taylor Fresh Food products have been impacted and that no branded salad kits contain iceberg lettuce, Taylor Farms said.
“As a family owned and operated company, we are deeply concerned for those who became ill, their families, and the many Americans whose trust in the safety of their fresh produce has been shaken. That trust is something we’ve worked for decades to earn, and we are committed to doing everything in our power to restore that confidence,” Taylor Farms said in a statement Friday.
Preliminary findings by Michigan health officials suggest lettuce or salad greens are the potential source of the illnesses. However, no specific type of produce, grower or supplier has been identified as the source, and federal health officials have not publicly identified a source of the outbreak.
The White House said on Thursday it is “closely monitoring” the cyclosporiasis outbreak and “has a handle on the situation.”
Press secretary Karoline Leavitt said the White House is working with the FDA and partners at the federal, state and local levels to “increase detection methods,” provide guidance and trace the outbreak.
On Tuesday, Taco Bell said it would voluntarily remove some ingredients at select restaurants as a precautionary measure.
“The health and safety of our guests is our top priority,” Taco Bell Corp said in a statement to ABC News. “Public health officials have not confirmed a link to Taco Bell or any specific ingredient, supplier, restaurant or retailer. While authorities continue their broader review, Taco Bell has voluntarily and temporarily removed limited ingredients at select restaurants as a precautionary measure. We will continue to closely monitor the situation and follow the guidance of public health authorities.“
Federal health officials said cases of cyclosporiasis will continue to rise in the U.S. The season is typically considered to be from May 1 to Aug. 31.
Additionally, the CDC sent out an alert to doctors around the country on Tuesday warning them of an increase in cases of cyclosporiasis.
Michigan health officials previously told ABC News the outbreak could be linked to food contamination.
Earlier this month, MDHHS sent out recommendations to restaurants and other commercial kitchens in southeast Michigan to reduce risks of exposure.
MDHHS data shows that most cases have been among adults, with 30 to 39 year olds making up the highest share.
The outbreak was first identified on June 29, when the Monroe County Health Department announced it was investigating a cluster of cases.
The parasite usually spreads through food or water contaminated with feces, according to the Centers for Disease Control and Prevention. It does not typically spread person-to-person.
Foodborne outbreaks of cyclosporiasis in the past have been linked to various types of imported fresh produce, such as raspberries, basil, snow peas, mesclun lettuce and cilantro, according to the CDC.
At least 31 other states have reported cases of cyclosporiasis, according to an ABC News tally, analyzing CDC data and state health department data.
Cyclosporiasis is treated with the oral antibiotic trimethoprim-sulfamethoxazole (TMP-SMX), commonly sold as Bactrim, Septra and Cotrim, and taken for 10 days, according to the CDC.
The agency says people can prevent infection by thoroughly washing produce, cutting away bruised or damaged parts of fruits and vegetables and refrigerating pre-prepared or pre-cut produce.
Additionally, the CDC recommends washing hands thoroughly with soap and water before handling or preparing raw fruits and vegetables.
ABC News’ Karen Travers contributed to this report.
Cyclospora cayetanensis is a unicellular parasite that causes an intestinal infection called cyclosporiasis. (CDC)
(NEW YORK) — Reported cases of cyclosporiasis, an intestinal illness caused by a parasite, have surpassed 2,600 in Michigan, the state’s health department said on Monday.
This is a developing story. Please check back for updates.