FDA approves breakthrough drug to treat advanced pancreatic cancer
FDA sign at its headquarters in Washington, D.C. (Getty Images stock photo/JHVEPhoto)
(WASHINGTON) — The Food and Drug Administration approved on Wednesday a drug that could extend the survival of those with metastatic pancreatic cancer.
The drug, called daraxonrasib, will be sold under the brand name Rasonque. The daily pill targets multiple forms of a protein called RAS, which is a main driver of tumor growth.
This is a developing story. Please check back for updates.
Cyclospora cayetanensis is a unicellular parasite that causes an intestinal infection called cyclosporiasis. (CDC)
(LANSING, Mich.) — Reported cases of cyclosporiasis, an intestinal illness caused by a parasite, have topped 1,200 in Michigan, local health officials said Thursday.
Since June 22, at least 1,251 cases have been confirmed, according to the Michigan Department of Health and Human Services (MDHHS) . At least 36 people have been hospitalized.
Typically, the state sees about 50 cases per year.
Dr. Natasha Bagdasarian, an infectious disease physician, epidemiologist and the chief medical executive for the state of Michigan, told ABC News earlier this week that the department’s working hypothesis is the outbreak is linked to contaminated produce.
The parasite usually spreads through food or water contaminated with feces, according to the Centers for Disease Control and Prevention (CDC).
Foodborne outbreaks of cyclosporiasis have been linked to various types of imported fresh produce, such as raspberries, basil, snow peas, mesclun lettuce and cilantro, according to the CDC.
The MDHHS spokesperson said on Wednesday that no specific produce, grower, supplier or type of produce has been identified as the source.
Michigan is not the only state reporting cases. The CDC said there have been 145 cases detected in 17 states since May 1, excluding Michigan. No deaths have been reported.
The CDC said patients’ ages cases ranged from 5 through 86 and 61% were female.
Some patients do not experience any symptoms but, for those who do, the most common symptom is “explosive watery diarrhea,” doctors previously told ABC News. Other symptoms can include cramping, bloating, low-grade fever, nausea and vomiting, the doctors said.
The CDC says it takes about one week from the time of infection to become symptomatic, but that time can range from two days to two weeks.
Because cyclosporiasis symptoms can resemble other illnesses, it may be hard for a patient to determine the cause.
“Anyone experiencing gastrointestinal illness, such as sudden and ongoing diarrhea, should contact their health care provider and their local health department,” the MDHHS spokesperson told ABC News in an email.
President Donald Trump has nominated Dr. Erica Schwartz, to be the Director of the CDC, April 16, 2026. (Department of Health and Human Services)
(WASHINGTON) — A confirmation hearing began on Wednesday for Dr. Erica Schwartz to be the next director of the Centers for Disease Control and Prevention (CDC).
Schwartz, a formal deputy surgeon general, was nominated by President Donald Trump in April. Trump made the announcement in a post on Truth Social, describing Schwartz as “incredibly talented.”
Schwartz is the fourth person named or nominated as head of the CDC since last summer. If confirmed by the Senate, Schwartz will replace Dr. Jay Bhattacharya, director of the National Institutes of Health, who took over as acting CDC director in February.
Schwartz earned a medical degree from Brown University and served in the U.S. Navy until 2005.
She served in the U.S. Public Health Service Commissioned Corps, as the Coast Guard Chief Medical Officer and as Deputy Surgeon General from 2019 to early 2021, during the first Trump administration.
“I was very pleased to see Dr. Schwartz nominated to be the next director of the CDC,” Dr. Richard Besser, former acting director of the CDC during the Obama administration, told ABC News. “What struck me is how refreshing it felt to see someone nominated for this job who actually has deep experience in public health and has the credentials necessary to lead a complex public health organization.”
Besser expressed concern about whether Schwartz, if confirmed, will have the independence from Health and Human Services Secretary Robert F. Kennedy Jr. to make public health recommendations, referencing a previous CDC director: Susan Monarez.
Monarez was confirmed as CDC director in July 2025, but she held the post for less than a month. Monarez was fired by Kennedy for reportedly not rubber-stamping the health secretary’s vaccine agenda or firing high-ranking CDC leaders whom he opposed.
The turmoil led to both Kennedy and Monarez appearing in front of Senate committees to address the ousting.
At a Senate hearing, Kennedy denied telling Monarez to accept vaccine recommendations without scientific evidence and claimed she was fired in part because she told him she was untrustworthy.
Besser said he expects that Schwartz will be asked by members of the Senate Committee on Health, Education, Labor and Pensions (HELP) about her perspectives on vaccinations, the Ebola outbreak in the Democratic Republic of the Congo and the rise of measles in the U.S.
“Those are some of the critical areas I think she’ll be asked about. There are so many other areas that are of concern to those who have relied on the CDC to prevent illness and promote health,” he said.
Sean Kaufman is also appearing before the Senate HELP Committee for his confirmation hearing on Wednesday. Kaufman was nominated to lead the Administration for Strategic Preparedness and Response, which was recently absorbed under CDC as part of an HHS reorganization in 2025.
Kaufman has claimed without evidence that the COVID-19 vaccine caused “excessive death and injury … in the United States and globally.” Health officials have said COVID-19 vaccines are safe and effective following clinical trials that involved tens of thousands of people and have since helped save millions of lives.
“What concerns me about Mr. Kaufman is that he has expressed very strong anti-vaccine views, and the ASPR is responsible for the strategic national stockpile,” Besser said. “So, I hope that the committee asks him questions to fully understand the approach that he would take in that role.”
Cyclospora cayetanensis is a unicellular parasite that causes an intestinal infection called cyclosporiasis. (CDC)
(NEW YORK) — Hospitalizations in Michigan linked to an outbreak of cyclosporiasis, an intestinal illness caused by a parasite, have surpassed 100, health officials said Friday.
So far, 102 people have been hospitalized, according to the Michigan Department of Health and Human Services (MDHHS). There are more than 5,000 cases in the state, an increase of nearly 700 since Thursday, officials said.
The Centers for Disease Control and Prevention and the Food and Drug Administration are warning consumers not to eat shredded iceberg lettuce sold at select Taco Bells in five states — Indiana, Kentucky, Michigan, Ohio, and West Virginia — after the ingredient was linked to the outbreak. The CDC said that shredded iceberg lettuce sold in grocery stores or served in other restaurants is not affected.
Lettuce supplier Taylor Farms said it is voluntarily removing all iceberg lettuce sourced from central Mexico from the U.S. market.
Taylor Farms said the FDA traceback indicated a “specific farm” that accounts for “less than 1% of the U.S.’s iceberg lettuce supply” was a potential source, and they have removed all iceberg lettuce from the region indefinitely. No other Taylor Fresh Food products have been impacted and that no branded salad kits contain iceberg lettuce, Taylor Farms said.
“As a family owned and operated company, we are deeply concerned for those who became ill, their families, and the many Americans whose trust in the safety of their fresh produce has been shaken. That trust is something we’ve worked for decades to earn, and we are committed to doing everything in our power to restore that confidence,” Taylor Farms said in a statement Friday.
Preliminary findings by Michigan health officials suggest lettuce or salad greens are the potential source of the illnesses. However, no specific type of produce, grower or supplier has been identified as the source, and federal health officials have not publicly identified a source of the outbreak.
The White House said on Thursday it is “closely monitoring” the cyclosporiasis outbreak and “has a handle on the situation.”
Press secretary Karoline Leavitt said the White House is working with the FDA and partners at the federal, state and local levels to “increase detection methods,” provide guidance and trace the outbreak.
On Tuesday, Taco Bell said it would voluntarily remove some ingredients at select restaurants as a precautionary measure.
“The health and safety of our guests is our top priority,” Taco Bell Corp said in a statement to ABC News. “Public health officials have not confirmed a link to Taco Bell or any specific ingredient, supplier, restaurant or retailer. While authorities continue their broader review, Taco Bell has voluntarily and temporarily removed limited ingredients at select restaurants as a precautionary measure. We will continue to closely monitor the situation and follow the guidance of public health authorities.“
Federal health officials said cases of cyclosporiasis will continue to rise in the U.S. The season is typically considered to be from May 1 to Aug. 31.
Additionally, the CDC sent out an alert to doctors around the country on Tuesday warning them of an increase in cases of cyclosporiasis.
Michigan health officials previously told ABC News the outbreak could be linked to food contamination.
Earlier this month, MDHHS sent out recommendations to restaurants and other commercial kitchens in southeast Michigan to reduce risks of exposure.
MDHHS data shows that most cases have been among adults, with 30 to 39 year olds making up the highest share.
The outbreak was first identified on June 29, when the Monroe County Health Department announced it was investigating a cluster of cases.
The parasite usually spreads through food or water contaminated with feces, according to the Centers for Disease Control and Prevention. It does not typically spread person-to-person.
Foodborne outbreaks of cyclosporiasis in the past have been linked to various types of imported fresh produce, such as raspberries, basil, snow peas, mesclun lettuce and cilantro, according to the CDC.
At least 31 other states have reported cases of cyclosporiasis, according to an ABC News tally, analyzing CDC data and state health department data.
Cyclosporiasis is treated with the oral antibiotic trimethoprim-sulfamethoxazole (TMP-SMX), commonly sold as Bactrim, Septra and Cotrim, and taken for 10 days, according to the CDC.
The agency says people can prevent infection by thoroughly washing produce, cutting away bruised or damaged parts of fruits and vegetables and refrigerating pre-prepared or pre-cut produce.
Additionally, the CDC recommends washing hands thoroughly with soap and water before handling or preparing raw fruits and vegetables.
ABC News’ Karen Travers contributed to this report.