Undiagnosed disease in Congo may be linked to malaria: Africa CDC
pawel.gaul/Getty Images
(NEW YORK) — A deadly, undiagnosed disease that has been spreading in one region of the Democratic Republic of Congo (DRC) may be linked to malaria, health officials said Thursday.
As of Dec. 14, the latest date for which data is available, 592 cases have been reported with 37 confirmed deaths and 44 deaths under investigation, according to the Africa Centres for Disease Control and Prevention (Africa CDC), the public health agency of the African Union.
Over the last week, 181 samples from 51 cases were tested in a laboratory, Dr. Ngashi Ngongo, Africa CDC chief of staff, said during a Thursday press briefing.
Laboratory testing showed 25 out of 29 tested were positive for malaria. Additionally, rapid testing showed 55 out of 88 patients were positive for malaria.
Ngashi said there are two hypotheses: The first is that the undiagnosed disease is severe malaria “on a background of malnutrition and viral infection” and the second is the disease is a viral infection “on a background of malaria and malnutrition.”
Malaria is a serious disease caused by a parasite that infects a certain type of mosquito, according to the U.S. Centers for Disease Control and Prevention (CDC). Most people contract malaria after being bitten by an infected mosquito.
Most cases of malaria occur in sub-Saharan Africa, but it also occurs in parts of Oceania and in parts of Central and South America and Southeast Asia.
Malaria can be deadly if is not diagnosed and treated quickly, the CDC said.
What we know about the disease
The disease first appeared in a remote area in the province of Kwango, in the southwestern part of the DRC on the border with Angola, according to Africa CDC.
The first case was documented on Oct. 24. Patients have been experiencing flu-like symptoms including fever, headache, coughing and difficulty breathing as well as anemia, Africa CDC said during a press briefing earlier this month.
A plurality of cases, or 42.7%, have occurred in children under 5 years old. This age group also has the largest number of deaths, with 21 so far, data from Africa CDC shows. Children between ages 5 and 9 make up the second highest number of cases
Africa CDC said in a post on X earlier this month that it took five to six weeks after the first case was reported for local authorities to alert the national government, highlighting “gaps in Africa’s disease detection systems: limited surveillance, testing delays & weak lab infrastructure.”
-ABC News’ Youri Benadjaoud contributed to this report.
(NEW YORK) — The U.S. Surgeon General issued an advisory on Friday warning of a link between alcohol consumption and cancer risk.
Alcohol consumption is the third leading preventable cause of cancer in the United States, after tobacco and obesity, according to the Surgeon General’s advisory.
For some cancers, including breast, mouth, and throat cancers, the risk of developing cancer may increase with one or fewer drinks per day, the advisory states.
Despite a growing body of evidence, fewer than half of Americans recognize alcohol consumption as a risk factor for cancer, according to the advisory.
A person’s risk of developing cancer due to alcohol consumption is also determined by other factors, including biological, economic, environmental and social, the advisory says.
“Alcohol is a well-established, preventable cause of cancer responsible for about 100,000 cases of cancer and 20,000 cancer deaths annually in the United States – greater than the 13,500 alcohol-associated traffic crash fatalities per year in the U.S. – yet the majority of Americans are unaware of this risk,” U.S. Surgeon General Dr. Vivek Murthy said in a statement. “This Advisory lays out steps we can all take to increase awareness of alcohol’s cancer risk and minimize harm.”
This is a developing story. Please check back for updates.
Hum Images/Universal Images Group via Getty Images
(NEW YORK) — As world leaders mourn the death of former President Jimmy Carter and remark on his political and policy legacy, doctors are remembering his efforts to prevent disease, and his legacy in furthering global public health.
The 39th president spent five decades working to eradicate a parasitic disease, helped organize a major-drug donation program, and made advancements addressing the mental health crisis in the U.S.
Dr. Julie Jacobson, currently a managing partner of the nonprofit Bridges to Development, helped to provide funding for the Carter Center’s work in the Americas, Nigeria and Ethiopia while she worked for the Bill & Melinda Gates Foundation for over a decade.
“He was hugely influential, I think particularly for the diseases that most of the world doesn’t appreciate even exist,” Jacobson told ABC News of Jimmy Carter’s work. “He was a true champion for the neglected tropical diseases, which are some of the most common infections of people who live with the least resources. And he found these diseases and then really wanted to do something about them, and used his voice, his influence, his passion, to continue to push forward where others were really not interested.”
Near-eradication of Guinea worm disease
Following his loss to Ronald Reagan in the 1980 presidential election, Carter founded the Carter Center in 1982, a non-profit organization that “seeks to prevent and resolve conflicts, enhance freedom and democracy, and improve health,” according to the Center’s website.
Among the organization’s many efforts, the Carter Center helped spearhead a successful international campaign with the goal of eradicating dracunculiasis, also known as Guinea worm disease, a parasitic infection caused by consuming contaminated drinking water.
Water from ponds or other stagnant bodies of water can contain tiny crustaceans commonly known as water fleas, which in turn can be infected with Guinea worm larvae, according to the Centers for Disease Control and Prevention (CDC).
About one year after infecting a human host, the Guinea worm creates a blister on the skin and emerges from it, which can cause burning pain, fever and swelling, according to the CDC and the World Health Organization.
“Nobody else wanted to take it on,” Jimmy Carter told ABC News’ George Stephanopoulos during a 2015 interview on “Good Morning America”. “So, I decided to take it on.”
In 1986, Guinea worm disease afflicted 3.5 million people every year in 21 African and Asian countries. Disease incidence has since been reduced by 99.99%, to just 14 “provisional” human cases in 2023, according to the Carter Center.
Jacobson said that success is even more remarkable because there are no vaccines available to prevent Guinea worm disease and no drugs to treat it. Tracking Guinea worm disease, according to Jacobson, involves following possible cases for a year to determine if they are infected, checking to see if infected humans have any infected water sources near them, and monitoring the community as a whole.
“To think that you could eradicate a disease without any tools is really still just a crazy idea, but he did it with perseverance and working with people in the grassroots within communities and putting together teams of people to go and work with people in those communities and empower the communities,” Jacobson said.
The Carter Center says if efforts are successful, Guinea worm disease could become the second human disease in history to be completely eradicated, after smallpox, and the first to be done without the use of a vaccine or medicine.
Carter told ABC News during the 2015 interview that eradicating the disease entirely was his goal: “I think this is going to be a great achievement for, not for me, but for the people that have been afflicted and for the entire world to see diseases like this eradicated.”
Mass drug distribution for river blindness
The Carter Center also works to fight other preventable diseases, including the parasitic infections schistosomiasis and lymphatic filariasis – more commonly known as snail fever and elephantiasis, respectively – as well as trachoma, which is one of the world’s leading causes of preventable blindness. It’s also working with the governments of Haiti and the Dominican Republic to eliminate lymphatic filariasis and malaria from the island of Hispaniola, which both countries share and which is “the last reservoir in the Caribbean for both diseases,” according to the Carter Center.
Carter and his organization also played a part in organizing a major drug-donation program to help eliminate onchocerciasis, also known as river blindness, which is transmitted to human through repeated bites of infected blackflies, according to the CDC.
Pharmaceutical company Merck & Co. had been implementing field studies in Africa which showed that the drug ivermectin was effective at treating river blindness in humans. The Carter Center partnered with Merck to mass-distribute ivermectin, brand name Mectizan, “as much as needed for as long as needed” in Africa and Latin America. To date, the Carter Center has assisted in distributing more than 500 million treatments of Mectizan, according to Merck.
In 1995, Carter negotiated a two-month cease-fire in Sudan to allow health care workers there to more safely help eradicate Guinea worm disease, prevent river blindness, and vaccinate children against polio.
“When we have known solutions, it is ethical to make sure they’re available to the people who need it most,” Dr. Usha Ramakrishnan, chair of the Department of Global Health at Emory University’s Rollins School of Public Health, told ABC News. “And that’s where we were with river blindness. There was a treatment, but improving access to medications, making it affordable, reaching the people they need was very much along the lines of the work [the Carter Center] was doing.”
Addressing mental health
Carter was also committed to tackling mental health issues. During his presidency, he created the Presidential Commission on Mental Health, which recommended a national plan to care for people with chronic mental illness.
Although it was never adopted as policy by the Reagan administration, the plan’s recommended strategies were adopted by some mental health advocacy groups to “make gains in the 1980s,” according to one study.
Carter also signed into law the Mental Health Systems Act of 1980, which provided funding to community mental health centers.
After his presidency, Carter and former first lady Rosalynn Carter continued working to improve access to mental health.
Ramakrishnan said the Carters’ work helped to reduce some of the stigma associated with mental health.
“There continues to be a lot of stigma, but they truly got it out [in] the conversation and mainstreaming mental health as an important aspect of health and well-being,” Ramakrishnan said. “There’s still a lot of challenges, and there are many capable people that they have mentored and trained who are carrying that mantle forward.”
(LOS ANGELES) — The percentage of emergency department (ED) visits related to fire and smoke inhalation rose dramatically in the days immediately after the Los Angeles wildfires last month, new data published Thursday shows.
The wildfires broke out in the Pacific Palisades and in Eaton Canyon on Jan. 7. Although several destructive wildfires emerged, the Palisades Fire and the Eaton Fire caused the most damage.
Fueled by strong winds and dry weather, the fires burned more than 57,000 acres, destroyed about 16,000 structures, and killed at least 29 people, according to the California Department of Forestry and Fire Protection.
A team from the Los Angeles County Department of Public Health and the Centers for Disease Control and Prevention reviewed data from the county’s Syndromic Surveillance program, which receives and analyzes real-time data from most county EDs.
By collecting this data, the program can detect early warning signals of a potential public health threat that requires a response and alert health care professionals, according to the department of health.
ED visits, referred to in the report as “encounters,” were classified as being wildfire-associated if fire or smoke inhalation–related terms were listed in the chief complaints or the diagnoses sections.
The team looked at three periods: a three-week period before the wildfires began, the first six days of the wildfires and the week after the wildfires began.
Data showed the average percentage of ED visits associated with the wildfires increased eightfold from 0.06% to 0.52% in the six days after the wildfires. The peak was seen on Jan. 8, with 1.01% of all ED visits related to the wildfires. During the week after the wildfires began, ED visits decreased but still remained elevated at 0.2% compared to baseline.
The average percentage of ED visits was found to be linked to an increase in the average daily Air Quality Index (AQI), which is put out by the Environmental Protection Agency.
Average daily AQI rose from 75, which is classified as “moderate level of concern” to an average of 110, classified as “unhealthy for sensitive groups,” in the six days after the wildfires began. In the week following the outbreak of the fires, average daily AQI returned to “moderate” at 58.
The report found a small increase in the average percentage of burn-related injuries and eye-related injuries but there were no increases seen in the percentage of visits related to asthma or cardiovascular reasons.
In contrast, the report found that immediately after the wildfires began, all-cause ED encounters — meaning visits to the department for any reason — decreased by 9%.
The authors stated that the decrease could for multiple reasons, with some including school closures, business closures, displacements, challenges accessing health care, residents seeking care in clinics or urgent care centers, or residents visiting EDs in neighboring counties.
“Near real-time surveillance of health outcomes during and after wildfires can estimate effects on health care use, serve as an early warning for acute health impacts, and identify opportunities for intervention,” the authors wrote. “Further analyses are planned to identify which illnesses have most affected specific populations.”
