Purdue Pharma, Sackler families boost contribution in opioid settlement to $7.4 billion
Purdue Pharma headquarters; Victor J. Blue/Bloomberg via Getty Images
(NEW YORK) — The company and once-prominent family behind the drug OxyContin agreed Thursday to increase their financial contribution to resolve mass opioid litigation.
The Sacklers and Purdue Pharma boosted their settlement contribution to $7.4 billion after the U.S. Supreme Court overturned a prior settlement in June 2024. If approved, the new plan would end the costliest corporate bankruptcy resulting from the U.S. opioid crisis.
Purdue, under the leadership of the Sackler families, invented, manufactured and aggressively marketed opioid products for decades, according to the lawsuits. States and cities across the country said it fueled waves of addiction and overdose deaths.
The pharmaceutical company introduced OxyContin, a brand name of oxycodone, in the 1990s and filed for chapter 11 bankruptcy in 2019 after the company was sued thousands of times.
Under the settlement terms, the Sacklers’ control of Purdue Pharma ends. The $7.4 billion will go directly to communities across the U.S. — including states, counties, cities and territories — over the next 15 years to support opioid addiction treatment, prevention, and recovery programs.
“Families throughout New York and across the nation are suffering from the immense pain and loss wrought by the opioid crisis,” said New York Attorney General Letitia James, whose office helped negotiate the settlement agreement.
“The Sackler family relentlessly pursued profit at the expense of vulnerable patients, and played a critical role in starting and fueling in the opioid epidemic,” she continued. “While no amount of money will ever fully repair the damage they caused, this massive influx of funds will bring resources to communities in need so that we can heal.”
Purdue Pharma planned to exit bankruptcy last year under terms that gave the Sacklers a full release from all civil opioid claims even though they themselves were not declaring bankruptcy. In return, the Sacklers agreed to pay $6 billion.
The Supreme Court rejected the attempt by the Sacklers to use Purdue Pharma’s bankruptcy to shield themselves from liability.
Under the new terms, a significant amount of the settlement funds will be distributed in the first three years, with the Sacklers paying $1.5 billion and Purdue paying nearly $900 million in the first payment, followed by $500 million after one year, an additional $500 million after two years, and $400 million after three years.
A board of trustees selected by participating states in consultation with the other creditors will determine the future of the company. Purdue will continue to be overseen by a monitor and will be prevented from lobbying or marketing opioids.
“This story is about a family of cruel billionaires who believed they were above the law, pursued by states who never backed down,” Connecticut Attorney General William Tong said Thursday. “Today, we are forcing Purdue Pharma and the Sackler family to pay $7.4 billion for their role in igniting one of the most devastating public health crises in American history.”
Purdue Pharma said in a statement to ABC News, “We are extremely pleased that a new agreement has been reached that will deliver billions of dollars to compensate victims, abate the opioid crisis, and deliver treatment and overdose rescue medicines that will save lives. We have worked intensely with our creditors for months in mediation, and we are now focused on finalizing the details of a new Plan of Reorganization, which we look forward to presenting to the bankruptcy court.”
(NEW YORK) — Some hospitals in the U.S. are seeing an increase in RSV and higher levels of “walking pneumonia” among young children despite overall respiratory illness activity remaining low nationally.
Cook Children’s Medical Centers in Texas reported a “steep increase” in children visiting the emergency room due to respiratory-related illnesses.
On Tuesday, at the health system’s Fort Worth location alone, there were 572 patients — a near-record-high number — in the emergency department. Officials said the increase in hospital visits is due to a spread of RSV and walking pneumonia in the Dallas-Fort Worth area.
Additionally, University of North Carolina hospitals reported 40 walking pneumonia cases in the last week of October compared to no cases the same time last year.
Infectious disease specialists say that although parents should stay alert when it comes to respiratory illnesses spreading, this season also may also be marking a return to typical seasons seen before the COVID-19 pandemic.
“It’s the calm before the storm,” Dr. Peter Chin-Hong, a professor of medicine and infectious disease specialist at the University of California, San Francisco, told ABC News. “It feels that there’s so much going on … that we almost forget about respiratory viruses, but they’re very regular. They’re kind of falling back into normal pre-pandemic cadence.”
Walking pneumonia seeing cyclical increase
So-called “walking pneumonia” is a respiratory tract bacterial infection caused by the bacteria Mycoplasma pneumoniae (M. pneumoniae), according to the Centers for Disease Control and Prevention.
Infections are generally mild, and people may seem better than expected for those with a lung infection, hence the term walking pneumonia, the CDC said. Sometimes serious complications, however, emerge requiring hospitalization.
For the week ending Nov. 2, the latest for which CDC data is available, 2.8% of all pneumonia-associated ED visits led to an M. pneumoniae diagnosis, up from just 2% at the end of September.
Rates were highest among those ages 1 and younger, making up 7.8% of all pneumonia-associated ED visits with an M. pneumoniae diagnosis for the week ending Nov. 2.
Experts say mycoplasma infections have a cyclical nature and tend to surge every three to seven years.
“Just like other respiratory viruses, there was not a lot of exposure during the pandemic years because of social distancing and people staying away from each other, and so we’re catching up to that,” Chin-Hong said. “Mycoplasma may also be one of these things where you’re kind of seeing the perfect storm. So, it comes back every four or five years and people are getting back to their normal lives.”
RSV activity returning to pre-pandemic levels
Respiratory syncytial virus, or RSV, is a common respiratory virus with most children affected by their second birthday, according to the CDC.
Although it typically causes mild, cold-like symptoms and most people recover in one to two weeks, it can be a serious infection for infants and older adults, resulting in hospitalization, the CDC said.
Current levels remain lower than those seen at the same time during the past few seasons.
“While RSV activity is increasing in certain regions, particularly among young children, it’s important to remember that we’re seeing a return to more typical pre-pandemic patterns,” said Dr. John Brownstein, an epidemiologist and chief innovation officer at Boston Children’s Hospital and an ABC News contributor.
“This year’s season is starting later and progressing more slowly compared to the past few years, which were marked by earlier and more severe outbreaks,” he added.
Brownstein pointed out that while national levels remain low, certain regions in the southern U.S. and eastern U.S. are seeing localized surges, especially among young children.
When to go to the emergency room
Chin-Hong said if symptoms are mild, including low-grade fever, dry cough, sore throat, headaches and mild aches and pains, parents can keep their children home and contact their primary care provider with any questions.
However, when symptoms become more severe including difficulty breathing, a long-lasting fever or lethargy, then it might be time to visit the emergency room.
If you have “a child who’s having a cough for more than seven days and maybe they’re not shaking that off, then you worry about something like walking pneumonia,” Chin-Hong said.
How to prevent RSV and walking pneumonia
To prevent RSV, there are three vaccines approved for adults ages 60 and older as well as some adults between the ages 50 and 59 who are at higher risk. There is also a vaccine available for pregnant women between 32 weeks and 36 weeks of pregnancy.
For babies under eight months, there are two monoclonal antibody products available. Monoclonal antibodies are proteins manufactured in a lab that mimic the antibodies the body naturally creates when fighting an infection.
“For walking pneumonia. or mycoplasma, there’s no vaccine for that, but by getting vaccines for RSV, COVID [and] influenza, you reduce the probability of co-infections that can make things worse,” Chin-Hong said.
Experts also recommended applying lessons learned during the COVID-19 pandemic, such as wearing a mask in spaces with poor ventilation.
“Practicing good hygiene, like frequent hand-washing and covering coughs and sneezes, remains essential in preventing the spread of respiratory infections,” Brownstein said.
At least 24 people are believed to be dead and more than a dozen others remain unaccounted for as of Monday morning. Additionally, 105,000 people remain under mandatory evacuation orders and another 87,000 are under evacuation warnings.
Kaiser Permanente, one of the largest health care systems in California, said most of its facilities remain open and operational but seven remain closed, including facilities in the cities and neighborhoods of Pasadena, Rosemead, Santa Monica, Canyon County and Sylmar.
Keck Medicine of USC shared an update to its website stating that all affiliated hospitals remain open but at least nine clinics remain closed, including those in Arcadia, Glendale, La Cañada Flintridge and Los Angeles.
Providence health care system, which serves five Western states including California, also announced that some of its outpatient services, such as doctors’ offices, were closed but that its hospitals remain open.
Adventist Health Glendale said in a statement on its website that its hospital and emergency department is operating as usual and patients are not being evacuated. However, some patients with elective procedures are being rescheduled to a later date and all non-essential visitation has been postponed.
“Some patients with elective procedures may be rescheduled for a later date – These patients will be contacted directly by their provider,” the statement said.
As of Sunday afternoon, UCLA Health said clinic operations were “impacted” in the neighborhoods of Calabasas, Malibu, Pacific Palisades and Pasadena. However, it’s unclear from the UCLA statement how many clinics are closed.
“Affected patients will be contacted with additional information. Patients with questions or seeking to reschedule appointments are encouraged to contact their physician’s office or clinic,” UCLA Health stated on its website. “UCLA Health asks that visits to our medical center emergency departments be reserved for urgent and life-threatening medical conditions.”
Some health care centers are working to reopen after being temporarily closed. Cedars-Sinai shared in an update on its website Monday that it was planning to resume non-urgent and non-emergency procedures, some of which it had postponed because of the fires.
“Our Medical Network has reopened most outpatient offices and surgery centers that had been temporarily closed, including locations in Brentwood/West Los Angeles, Los Feliz, Pasadena and Santa Monica. We continue to do everything possible to minimize any disruptions to care,” Cedars-Sinai’s update stated.
Additionally, City of Hope Comprehensive Cancer Center, which has locations in four states including California, said its main campus in Duarte and all of its outpatient clinics are open as staff work to accommodate patients “whose care was impacted over the last few days.”
(NEW YORK) — Authorities are looking into online accounts believed to be those of Luigi Mangione, the 26-year-old Ivy League graduate charged with murder in the fatal shooting of UnitedHealthcare CEO Brian Thompson on a Manhattan street, that have posted about health struggles and possible medical successes.
Mangione appeared to operate a Reddit profile where he detailed health issues including back pain, brain fog and sciatica. The account made several posts on a subreddit dedicated to spondylolisthesis — a condition where a vertebra slips out of alignment. Mangione also might have planned to read or already read multiple books on back pain based on a Goodreads account associated with him.
Law enforcement sources have told ABC News that the Reddit profile — which has since been taken down — is being reviewed for additional details about the extent of the injuries mentioned. A Reddit spokesperson told ABC News regarding the page that their policy is to suspend accounts that may potentially be related to suspects in high-profile criminal investigations.
Mangione is accused of gunning down Thompson outside a Midtown Manhattan hotel on Dec. 4. Written on the shell casings were the words “deny,” “defend” and “depose,” according to police sources. Mangione was apprehended in Altoona, Pennsylvania, on Monday after nearly one week on the run. He allegedly had a spiral notebook detailing plans about how to eventually kill the CEO, according to law enforcement officials.
Mangione is being held without bail in Pennsylvania, where he faces charges including allegedly possessing an untraceable ghost gun. Defense attorney Thomas Dickey told reporters on Tuesday that Mangione will plead not guilty to the Pennsylvania charges. He said he anticipates that Mangione will also plead not guilty to the second-degree murder charge in New York.
The posts and reading lists paint a picture of someone seeking answers, sharing how spinal fusion surgery brought the author relief after years of discomfort.
“Chronic pain can be incredibly debilitating. It can affect every aspect of your life,” Dr. Joseph Shrand, chief medical officer of Riverside Community Care in Massachusetts and a Harvard Medical School faculty member, told ABC News.
While the Reddit posts suggest a spinal surgery was a significant moment in his life, the author of the posts said the procedure left him pain-free, and he frequently encouraged others to undertake similar procedures.
In an August 2023 post, the user remarked how his spinal injury was once “completely devastating” and worried he was “destined to chronic pain and a desk job for the rest of my life” before considering surgery.
Chronic pain, defined as pain lasting three months or more, affects about 50 million U.S. adults, according to the National Institutes of Health. Of these, 17 million Americans experience “high impact” chronic pain, which is so debilitating that it disrupts daily activities like work, self-care and relationships, the NIH says.
Women, older adults, and those living in poverty or rural areas tend to report the highest rates of persistent pain. So do people who are divorced or separated, identify as bisexual, or say they are generally in poor health, according to the NIH.
Studies suggest that chronic pain can put people at a higher risk of mental health struggles, as well as create a financial burden.
Research shows that between 35% to 45% of those with chronic pain experience depression, while anxiety disorders are similarly common. Pain may interfere with sleep, increase stress, and create cycles of declining mental and physical health.
“Chronic pain puts you at a disadvantage mentally because you may think other people see you as broken,” Shrand said. “There will be times where you may feel in such physical pain that it becomes emotional pain, too.”
Some studies suggest a biological link between chronic pain and mental health disorders. For example, depression can heighten pain sensitivity, reinforcing the connection between the two, according to a study in the journal Neural Plasticity.
Chronic pain affects every facet of life. It can limit employment opportunities, disrupt social connections and lead to cognitive challenges, including “brain fog.”
“People have difficulty getting out of bed in the morning because their backs hurt, which means that they’re potentially at risk of coming into work late, which then puts them at risk for the cascade effects of all those things that can happen because they are now perceived as a person who isn’t doing their job right,” Shrand said.
Chronic pain can lead to a substantial financial burden, as well. According to one Journal of Pain study, individuals with severe pain spend more than $4,000 more annually on health care versus those without pain.
Managing chronic pain requires a combination of medical, psychological and lifestyle interventions, but insurance often prioritizes medications and procedures with inconsistent results.
For instance, lumbar fusion surgeries — such as the one purportedly described by Mangione — are commonly performed but often fail to provide lasting relief, according to various studies.
When Mangione was arrested on Monday, he had “written admissions about the crime” with him, according to the New York arrest warrant.
Mangione had several handwritten pages on him that expressed a “disdain for corporate America” and indicated “he’s frustrated with the health care system in the United States,” NYPD Chief of Detectives Joe Kenny told ABC News’ “Good Morning America” on Tuesday.
The words on the bullets echo the title of the 2010 book “Delay, Deny, Defend: Why Insurance Companies Don’t Pay Claims and What You Can Do About It.” Police are aware of the similarity, and are investigating whether one possible motive is anger at the insurance industry, sources said.
While the Reddit posts suggest a spinal surgery was a significant moment in his life, the author of the posts said the procedure left him pain-free, and he frequently encouraged others to undertake similar procedures.
One of Mangione’s apparent posts on the r/Spondylolisthesis subreddit in February 2024 referred to having had a surgery for the condition six months prior. The author said that “[w]within 7 days of the fusion I was on zero pain meds.”
Many widely used approaches, such as opioids or steroid injections, provide only temporary solutions to chronic pain. Meanwhile, treatments like cognitive behavioral therapy, yoga and acceptance therapy show promise but remain difficult to access due to cost and insurance coverage gaps.
However, many chronic pain patients face a maze of treatments that don’t fully address their needs or the root causes of their pain.
Shrand said the best approach often requires a combination of solutions.
“You can’t just attack the physical. You’ve got to address the biological, mental and social aspects of life,” he said. “You can manage this pain — it’s part of your body, and we can find a way to take care of you.”
ABC News’ Peter Charalambous, Aaron Katersky, Kerem Inal, Chris Looft and Sasha Pezenik contributed to this report.
