At least 24 people are believed to be dead and more than a dozen others remain unaccounted for as of Monday morning. Additionally, 105,000 people remain under mandatory evacuation orders and another 87,000 are under evacuation warnings.
Kaiser Permanente, one of the largest health care systems in California, said most of its facilities remain open and operational but seven remain closed, including facilities in the cities and neighborhoods of Pasadena, Rosemead, Santa Monica, Canyon County and Sylmar.
Keck Medicine of USC shared an update to its website stating that all affiliated hospitals remain open but at least nine clinics remain closed, including those in Arcadia, Glendale, La Cañada Flintridge and Los Angeles.
Providence health care system, which serves five Western states including California, also announced that some of its outpatient services, such as doctors’ offices, were closed but that its hospitals remain open.
Adventist Health Glendale said in a statement on its website that its hospital and emergency department is operating as usual and patients are not being evacuated. However, some patients with elective procedures are being rescheduled to a later date and all non-essential visitation has been postponed.
“Some patients with elective procedures may be rescheduled for a later date – These patients will be contacted directly by their provider,” the statement said.
As of Sunday afternoon, UCLA Health said clinic operations were “impacted” in the neighborhoods of Calabasas, Malibu, Pacific Palisades and Pasadena. However, it’s unclear from the UCLA statement how many clinics are closed.
“Affected patients will be contacted with additional information. Patients with questions or seeking to reschedule appointments are encouraged to contact their physician’s office or clinic,” UCLA Health stated on its website. “UCLA Health asks that visits to our medical center emergency departments be reserved for urgent and life-threatening medical conditions.”
Some health care centers are working to reopen after being temporarily closed. Cedars-Sinai shared in an update on its website Monday that it was planning to resume non-urgent and non-emergency procedures, some of which it had postponed because of the fires.
“Our Medical Network has reopened most outpatient offices and surgery centers that had been temporarily closed, including locations in Brentwood/West Los Angeles, Los Feliz, Pasadena and Santa Monica. We continue to do everything possible to minimize any disruptions to care,” Cedars-Sinai’s update stated.
Additionally, City of Hope Comprehensive Cancer Center, which has locations in four states including California, said its main campus in Duarte and all of its outpatient clinics are open as staff work to accommodate patients “whose care was impacted over the last few days.”
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(NEW YORK) — As world leaders mourn the death of former President Jimmy Carter and remark on his political and policy legacy, doctors are remembering his efforts to prevent disease, and his legacy in furthering global public health.
The 39th president spent five decades working to eradicate a parasitic disease, helped organize a major-drug donation program, and made advancements addressing the mental health crisis in the U.S.
Dr. Julie Jacobson, currently a managing partner of the nonprofit Bridges to Development, helped to provide funding for the Carter Center’s work in the Americas, Nigeria and Ethiopia while she worked for the Bill & Melinda Gates Foundation for over a decade.
“He was hugely influential, I think particularly for the diseases that most of the world doesn’t appreciate even exist,” Jacobson told ABC News of Jimmy Carter’s work. “He was a true champion for the neglected tropical diseases, which are some of the most common infections of people who live with the least resources. And he found these diseases and then really wanted to do something about them, and used his voice, his influence, his passion, to continue to push forward where others were really not interested.”
Near-eradication of Guinea worm disease
Following his loss to Ronald Reagan in the 1980 presidential election, Carter founded the Carter Center in 1982, a non-profit organization that “seeks to prevent and resolve conflicts, enhance freedom and democracy, and improve health,” according to the Center’s website.
Among the organization’s many efforts, the Carter Center helped spearhead a successful international campaign with the goal of eradicating dracunculiasis, also known as Guinea worm disease, a parasitic infection caused by consuming contaminated drinking water.
Water from ponds or other stagnant bodies of water can contain tiny crustaceans commonly known as water fleas, which in turn can be infected with Guinea worm larvae, according to the Centers for Disease Control and Prevention (CDC).
About one year after infecting a human host, the Guinea worm creates a blister on the skin and emerges from it, which can cause burning pain, fever and swelling, according to the CDC and the World Health Organization.
“Nobody else wanted to take it on,” Jimmy Carter told ABC News’ George Stephanopoulos during a 2015 interview on “Good Morning America”. “So, I decided to take it on.”
In 1986, Guinea worm disease afflicted 3.5 million people every year in 21 African and Asian countries. Disease incidence has since been reduced by 99.99%, to just 14 “provisional” human cases in 2023, according to the Carter Center.
Jacobson said that success is even more remarkable because there are no vaccines available to prevent Guinea worm disease and no drugs to treat it. Tracking Guinea worm disease, according to Jacobson, involves following possible cases for a year to determine if they are infected, checking to see if infected humans have any infected water sources near them, and monitoring the community as a whole.
“To think that you could eradicate a disease without any tools is really still just a crazy idea, but he did it with perseverance and working with people in the grassroots within communities and putting together teams of people to go and work with people in those communities and empower the communities,” Jacobson said.
The Carter Center says if efforts are successful, Guinea worm disease could become the second human disease in history to be completely eradicated, after smallpox, and the first to be done without the use of a vaccine or medicine.
Carter told ABC News during the 2015 interview that eradicating the disease entirely was his goal: “I think this is going to be a great achievement for, not for me, but for the people that have been afflicted and for the entire world to see diseases like this eradicated.”
Mass drug distribution for river blindness
The Carter Center also works to fight other preventable diseases, including the parasitic infections schistosomiasis and lymphatic filariasis – more commonly known as snail fever and elephantiasis, respectively – as well as trachoma, which is one of the world’s leading causes of preventable blindness. It’s also working with the governments of Haiti and the Dominican Republic to eliminate lymphatic filariasis and malaria from the island of Hispaniola, which both countries share and which is “the last reservoir in the Caribbean for both diseases,” according to the Carter Center.
Carter and his organization also played a part in organizing a major drug-donation program to help eliminate onchocerciasis, also known as river blindness, which is transmitted to human through repeated bites of infected blackflies, according to the CDC.
Pharmaceutical company Merck & Co. had been implementing field studies in Africa which showed that the drug ivermectin was effective at treating river blindness in humans. The Carter Center partnered with Merck to mass-distribute ivermectin, brand name Mectizan, “as much as needed for as long as needed” in Africa and Latin America. To date, the Carter Center has assisted in distributing more than 500 million treatments of Mectizan, according to Merck.
In 1995, Carter negotiated a two-month cease-fire in Sudan to allow health care workers there to more safely help eradicate Guinea worm disease, prevent river blindness, and vaccinate children against polio.
“When we have known solutions, it is ethical to make sure they’re available to the people who need it most,” Dr. Usha Ramakrishnan, chair of the Department of Global Health at Emory University’s Rollins School of Public Health, told ABC News. “And that’s where we were with river blindness. There was a treatment, but improving access to medications, making it affordable, reaching the people they need was very much along the lines of the work [the Carter Center] was doing.”
Addressing mental health
Carter was also committed to tackling mental health issues. During his presidency, he created the Presidential Commission on Mental Health, which recommended a national plan to care for people with chronic mental illness.
Although it was never adopted as policy by the Reagan administration, the plan’s recommended strategies were adopted by some mental health advocacy groups to “make gains in the 1980s,” according to one study.
Carter also signed into law the Mental Health Systems Act of 1980, which provided funding to community mental health centers.
After his presidency, Carter and former first lady Rosalynn Carter continued working to improve access to mental health.
Ramakrishnan said the Carters’ work helped to reduce some of the stigma associated with mental health.
“There continues to be a lot of stigma, but they truly got it out [in] the conversation and mainstreaming mental health as an important aspect of health and well-being,” Ramakrishnan said. “There’s still a lot of challenges, and there are many capable people that they have mentored and trained who are carrying that mantle forward.”
(NEW YORK) — Women are now being diagnosed with cancer more often than men in certain age groups, according to a new report from the American Cancer Society.
Among adults aged 50-64, cancer rates are slightly higher in women, and women under 50 are almost twice as likely as men in the same age group to receive a cancer diagnosis.
The report, released Thursday, found that while deaths continue to decrease, troubling racial disparities persist, with white Americans more likely to survive cancer than other groups.
Meanwhile, the report echoed data from recent years suggesting a worrying increase in cancer diagnosis among younger Americans, with colon cancer rates increasing among adults 65 and younger.
Broadly, the report suggested doctors are getting better at saving lives thanks to better treatments but reinforced worrying trends around rising diagnoses of some cancers, particularly among women. Changes in screening practices, lifestyle factors, obesity, environmental hazards and lower rates of smoking in men may be contributing to the trend, the report said.
Alcohol in particular was singled out as a possible lifestyle factor that may increase the risk of some cancers.
“For colorectal cancer, for example, it seems to be really excessive [alcohol intake] that is associated with increased risk of this cancer, whereas for breast cancer, there doesn’t seem to be any safe level of alcohol, but the elevated risk is small,” said Rebecca Seigel, senior scientific director of cancer surveillance research for the American Cancer Society.
As Seigel explained, higher rates of cancer in young people could also be part of a “generational impact” where people are diagnosed earlier in life and less frequently when they are older.
Lung cancer remains particularly deadly, with 2.5 times more deaths than colorectal and pancreatic cancer. Smoking continues to be the leading preventable cause of lung cancer, but other contributors, such as radon, air pollution and genetic mutations, may be driving cases.
“Overall, in this country, nonsmoking lung cancer, by itself, would be the eighth leading cause of cancer mortality, and worldwide, it would be the fifth leading,” said Dr. William Dahut, the American Cancer Society’s chief science officer.
Disparity rates in cancer outcomes remain striking as well, especially for minority populations.
Uterine corpus cancer, for example, has lower survival rates now than 40 years ago, with Black women at 63% survival compared to 84% for white women. Black men and women also face some of the highest death rates for prostate and breast cancers.
“I think the stubborn resistance in terms of outcomes among underrepresented minorities is a concern,” said Dr. Wayne A. I. Frederick, interim chief executive officer of the American Cancer Society.
“We have our VOICES program, which is an attempt to enroll as many African American women from across the country in a longitudinal study, something that hasn’t been done to try to answer some of these questions as to why that persistent burden is there,” he added.
The report does include some good news. While it predicts around 1,700 deaths from cancer per day in 2025, cancer death rates have fallen by 34% since their peak in 1991, preventing nearly 4.5 million deaths over the past three decades. This progress is largely attributed to declines in smoking, earlier detection for certain cancers, and advances in treatment, including breakthrough therapies like immunotherapy and targeted drugs.
Prevention has been a critical focus too, with initiatives like smoking cessation programs and HPV vaccination playing pivotal roles in reducing cancer risk. Public health efforts targeting obesity, alcohol use and expanding access to screenings have also helped tackle preventable cancers by improving early detection.
Cancer experts stress the importance of staying current with screening recommendations. For example, the American Cancer Society recommends most people start screening for colorectal cancer at age 45 or even sooner if you have a family history. For breast cancer, mammogram screening should start at age 40 for women with normal risk and earlier for women at high risk.
The report is a call for people to understand their family history better and take steps to reduce cancer risk, Dahut noted.
“Being proactive on your diet, on your exercise, avoiding tobacco, getting your vaccinations and monitoring alcohol are really all important ways to actually prevent cancer,” he said, adding that research efforts are also focused on finding new ways to detect cancer.
Miranda Guerriero, D.O., is a resident physician at University of Texas at Tyler and a member of the ABC News Medical Unit.
Jessie Owen was left paralyzed nearly 12 years ago when a tree fell on a car in which she was a passenger. Via ABC News.
(NEW YORK) — Nearly 12 years ago, Jessie Owen’s life changed forever.
“My family was going over a mountain pass and a tree fell on our car. In that moment, my parents passed away, my siblings were severely injured, and I became quadriplegic,” Owen said. “I lost my independence. I lost my job. I lost my apartment. I lost my autonomy and the life that I dreamed for myself.”
Like Owen, more than 300,000 people live with spinal cord injuries in the United States, with an estimated 18,000 new cases each year, data shows.
Motor vehicle accidents account for the majority of spinal cord injuries and are closely followed by falls, acts of violence and sports activities, according to the National Spinal Cord Injury Statistical Center.
For years, options for recovery have been limited, but a newly FDA-cleared external spinal stimulator, ARC-EX Therapy, which received clearance on Dec. 19, may offer hope for people like Owen.
“ARC-EX is simply electrodes attached to skin on the back of the neck,” explained Chet Moritz, M.D., a professor of rehabilitation medicine at the University of Washington. “It allows us to pass current through the skin to activate the sensory nerves as they enter the spinal cord. Now, those sensory nerves make direct connections to the motor nerves which help people to move.”
Owen, who participated in the Up-LIFT study, a clinical trial focusing on the health benefits of ARC-EX Therapy, saw a life-changing impact.
“I was wildly surprised and pleased to see that it was making meaningful change in my life. I can now paint with my hands. I can open a jar of peanut butter. I can tie my shoes. It [used to] take me 30 minutes to get dressed. Now it takes 12. [I used to require] 20 caregiving hours a week and I was able to move down to about eight.”
The Up-LIFT study produced promising results.
Of the 60 patients with cervical spinal cord injuries studied, 72% saw improvements in hand strength and function. Participants also reported fewer muscle spasms, better sleep, less pain, and improved independence during daily activities.
“The success of [this] study of people with spinal cord injuries is phenomenal,” noted Moritz. “There are essentially no current therapies for chronic spinal cord injury, and so having the majority of patients respond in both strength and function measures [is] just an outstanding result.”
With FDA approval, ARC-EX Therapy is expected to become more accessible.
“Patients can work with their local rehabilitation clinics to see a therapist and work with them in the clinic at first to tune the device,” Moritz said. Results may appear quickly — some participants noticed changes within just a few sessions, he added.
While the device is currently cleared for improving hand strength, function and sensation, Moritz noted other benefits: “Some people will have modest improvements in their bladder function, heart rate, or blood pressure control.”
Leah Croll, M.D., vascular neurologist at Maimonides Health and assistant professor of neurology at SUNY Downstate, shared the excitement over the device.
“The idea that ARC-EX Therapy may accelerate or augment neurologic recovery is really exciting. Any improvement in neurologic function is meaningful and has far-reaching impact in the daily lives of these patients and their families,” she said.
The road to recovery after a spinal cord injury is grueling, Croll said.
“After emergency and ICU care is completed, the mainstay of treatment is working closely with physical therapists, occupational therapists and other rehabilitation professionals to support neurologic recovery,” said Croll. “Patients may also need medications and certain procedures, depending on their unique symptoms.”
For Owen and others, ARC-EX Therapy represents a renewed sense of hope and an exciting change in the way these patients can be treated.
“[With ARC-EX Therapy], I continued to gain function back, and I found I was able to pour more into other people,” Owen said. “The first indicator of success that I noticed was my own happiness. It works, and it gives us hope and passion.”
Natalie S. Rosen, M.D., is a physician in the Hematology & Oncology Department at New York-Presbyterian Columbia and a member of the ABC News Medical Unit.
