US reports highest number of measles cases since 2019: CDC

(LUBBOCK, TEXAS) — A second child in Texas has died of measles, according to the Texas Department of State Health Services.

“The school-aged child who tested positive for measles was hospitalized in Lubbock and passed away on Thursday from what the child’s doctors described as measles pulmonary failure,” the statement said, in part. “The child was not vaccinated and had no reported underlying conditions.”

The University Medical Center in Lubbock, Texas, said the child had been receiving care for “complications of measles while hospitalized” and also emphasized, as the state health department did, that the child was unvaccinated with no underlying conditions.

An unvaccinated school-aged child also died of measles in Texas in late February, according to the Texas Department of Health Services – the first measles death in a decade in the United States. A week later, an unvaccinated adult in New Mexico died with measles, the New Mexico Department of Health reported.

The outbreak has so far led to 642 confirmed cases across 22 states, but the vast majority — 499 cases — have been in Texas, Health and Human Services Secretary Robert F. Kennedy posted on X on Sunday afternoon.

Kennedy also said in the post that he visited Texas on Sunday to “comfort” the family of the child. He said he’d developed a close relationship with the impacted community — which has largely been unvaccinated — including the family of the first child to die in the outbreak.

He added that the “most effective way to prevent the spread of measles” is the measles, mumps and rubella — or MMR — vaccine.

The HHS secretary, who has a long history of vaccine skepticism, has come under fire from public health officials for downplaying the measles outbreak and not advocating enough for widespread vaccination.

In Kennedy’s first public comments on the measles outbreak last month, he said that outbreaks were not “uncommon” because they happen every year and declined to specifically encourage vaccination.

Public health experts who criticized Kennedy pointed out that outbreaks do not have to happen every year and are preventable with the MMR vaccine, which is 97% effective with two doses. Kennedy has since repeated that the vaccine is the “most effective way” to prevent measles, though often also noted that it’s a “personal choice.”

Republican Sen. Bill Cassidy, a physician who publicly wrestled with his support for Kennedy but eventually voted to support him as HHS secretary, said the second death in Texas proved that “top health officials” should be “unequivocally” encouraging the vaccine.

“Everyone should be vaccinated!” Cassidy wrote on X Sunday. “There is no treatment for measles. No benefit to getting measles. Top health officials should say so unequivocally [before] another child dies.”

The Texas Department of State Health Services said on April 4 that Texas is experiencing its worst measles outbreak in 30 years.

There are more than double the number of cases of measles in the U.S. in the first quarter of this year than the entirety of last year, which saw 285 cases nationwide, according to the Centers for Disease Control and Prevention.

These are the highest number of measles cases in the U.S. since 2019, which saw 1,274 cases, according to the CDC. New Mexico is experiencing its worst measles outbreak in 40 years, with 54 cases. Kansas and Ohio are also experiencing outbreaks.

If the number of this year’s cases continues to grow at the current rate, the U.S. would likely surpass that 2019 number, which would lead to the highest number of cases in the U.S. since 1992.

The U.S. declared measles eliminated in the year 2000, after finding no continuous spread of the highly contagious disease over 12 months. The country would be at risk of losing that status if an outbreak continued for more than one year. The Texas outbreak saw its first measles cases in January.

The CDC currently recommends that people receive two doses of the MMR vaccine, the first at ages 12 to 15 months and the second between 4 and 6 years old. One dose is 93% effective, and two doses are 97% effective against measles.

In his statement on Sunday, Kennedy said a CDC team was deployed to Texas in early March to support state and local health officials and to supply pharmacies and clinics with MMR vaccines.

“I’ve spoken to Governor Abbott, and I’ve offered HHS’ continued support. At his request, we have redeployed CDC teams to Texas. We will continue to follow Texas’ lead and to offer similar resources to other affected jurisdictions,” he said in the post.

Kennedy’ visit to Texas comes shortly after the secretary, a prominent vaccine skeptic, has cut one-fourth of the HHS workforce and one-fifth of those employed by the CDC.

The HHS recently clawed back roughly $11 billion in funding from state and local health departments for COVID recovery efforts, saying the money was no longer needed as the pandemic was over. But health officials said the money was being used to better equip communities’ abilities to deal with the spread of diseases — including measles — and better prepare for the next pandemic.

Dr. Philip Huang, the top health official for the city of Dallas, told ABC News that the cuts to the HHS funding and its workforce could impact efforts to respond to the measles outbreak in his state.

“This definitely impacts our measles response,” he said. “We were looking to build out our lab capacity, some of our ability to get immunizations out into the community and into schools.”

“These smaller health departments, they don’t have many staff. You make a small cut and that takes away a considerable percentage of their workforce and ability to respond to anything at all,” Huang said.

ABC News’ Benjamin Siegel contributed to this report.

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(WASHINGTON) — Five years ago, the World Health Organization declared the COVID-19 outbreak to be a pandemic, leading to stay at-home orders and shutdowns across the U.S. and world.

The nation looks much different since then, and scientists and researchers have learned a lot about the virus, including how it infects people, the best forms of treatment and what puts someone at risk for long COVID.

There are still many questions, however. Health care professionals are working to find answers, such as how many people have truly died, how long the virus spread undetected in the U.S. and its origins.

“We know this emerged in China, around the city Wuhan. That’s very clear,” Dr. Cameron Wolfe, an infectious diseases specialist and a professor of medicine at Duke University School of Medicine, told ABC News. “We know when [the] medical community identified it, but we don’t know quite how long it was circulating before then. I think it’s caused some of the consternation.”

How many people have died of COVID-19?

As of March 6, at least 1,222,603 Americans have died of COVID-19, according to data from the Centers for Disease Control and Prevention.

The U.S. currently has the highest number of deaths of any country in the world, according to the WHO.

Experts, however, believe the true death toll is higher.

“More than a million people is a tragedy into itself, let’s start with that obvious fact,” Wolfe said. “I think the numbers are really hard to pin down for one key reason.”

Determining the exact cause of death can be complicated, Wolfe explained. Someone could die of COVID pneumonia — a lung infection caused by the virus — or die from a heart attack after contracting COVID.

Another example is an older adult who contracts COVID-19. They may become dehydrated, break a bone — because dehydration negatively impacts bone health — and suffer fatal complications, Wolfe said.

“How you count those outcomes is really important because, to me, that person wouldn’t have had their heart attack or that person wouldn’t have become dehydrated and fallen over and landed in the hospital if not for COVID triggering that event in the first place,” he said. “So, I actually think it’s really important to count those as COVID-associated mortalities, but they’re hard to count. They’re hard to track.”

Globally, more than 7 million people have died due to COVID-19, WHO data shows, although the agency says the pandemic caused an estimated 14.83 million excess deaths around the world in 2020 and 2021.

What is the mechanism behind long COVID

Scientists are not sure what causes long COVID but have identified certain risk factors such as an underlying health condition. Long-COVID symptoms can last for weeks, months or even years and can include — but are not limited to — fever, fatigue, coughing, chest pain, headaches, difficulty concentrating, sleep problems, stomach pain and joint or muscle pain, according to the CDC.

Research has found that patients with long COVID tend to have lower cortisol levels and lower testosterone levels.

“There are several questions that we still do not have answers for. What is the mechanism of the disease? Why do some people get more sick than others?” Dr. Fernando Carnavali, an internal medicine physician and a member of the team at Mount Sinai’s Center for Post-COVID Care, told ABC News.

Carnavali said scientists are using machine learning to study groups of long COVID patients in an attempt to determine the mechanisms that cause the condition.

“Do we have a single answer? Not as of yet, and most likely, perhaps we’ll have more than one answer,” he said.

Carnavali said the mechanism may not be the same for every long COVID patient. Additionally, people may have different symptoms due to different genetic predispositions.

“Some of the deficits that we have five years ago still remain, but I think that we should all understand and be hopeful that … researchers using machine learning will [provide] us some of the answers that we need as clinicians,” he said.

When did COVID enter the United States?

It’s still not exactly clear when the virus first entered the U.S. The first confirmed case in the country was Jan. 20, 2020, in a man in his 30s in Washington state, who developed symptoms after a trip to Wuhan.

However, studies have suggested the virus may have been circulating undetected for months beforehand.

Although the WHO was first notified on Dec. 31, 2019, about the mysterious pneumonia-like illness that originated in Wuhan, experts say it is likely that in an age of global travel, the virus was in the U.S. before then.

“It’s more likely circulated before Jan. 1 [2020]. It doesn’t seem unreasonable, November, December,” Dr. Lisa Olson-Gugerty, an associate teaching professor for Syracuse University and practicing family nurse practitioner in emergency medicine, told ABC News. “COVID masquerades itself as a flu-like illness, upper respiratory-like illness, like many other viral illnesses. It’s not easy to say, ‘Hey, I think this must be a new thing, and I’m going to tell everyone.'”

She went on, “I think it takes a bit of collective time to recognize a new viral strain, and it doesn’t seem unreasonable [there were] cases that could have been recognized as COVID before the date of release of information.”

Where did the virus come from?

There are two theories about where the virus, known as SARS-CoV-2, originated.

At least four U.S. agencies believe the virus was a result of natural transmission and that the virus jumped from animals to humans at a wet market.

The FBI, the CIA and the Department of Energy – the latter with “low confidence” — believe the COVID-19 pandemic “most likely” was the result of a laboratory leak in China.

Additionally, an April 2023 report from Senate Republicans conceded that “both hypotheses are plausible” but that the evidence points to the virus emerging from an accidental lab leak in Wuhan — and there may even have been multiple leaks.

If the virus did come from an animal, there are questions about which species may have spilled the virus over from animals to humans.

“I’ve seen a lot of conflicting information,” Olson-Gugerty said. “Did it come from a bat? Did it get into raccoon dogs or civet cats? Or was it a lab-created virus in Wuhan, China There does seem to be a jury that’s out.”

Wolfe said we may never know the true origins of SARS-CoV-2, but trying to answer the question helps scientists and public health professionals learn how to mitigate the spread so a pandemic — or even widespread illness — doesn’t happen again.

“This was the same question that happened during the Ebola pandemic, when we had to say, ‘Where did this come from? How can we educate people to minimize this future risk?'” he said. “It was important to examine where COVID-19 came from to try and put things in place that would stop that happening.”

He added, “We certainly, I would say, have better safety mechanisms now in place … so there are some good things that have come out of this.”

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(WASHINGTON) — The Department of Health and Human Services and the Food and Drug Administration announced on Tuesday a series of measures to phase out eight artificial food dyes and colorings from America’s food supply by the end of next year.

Speaking at a news conference, FDA Commissioner Dr. Marty Makary said the agencies are looking to revoke authorization for two synthetic food colorings and to eliminate six remaining synthetic dyes used in cereal, ice cream, snacks, yogurts and more.

“Today, the FDA is taking action to remove petroleum-based food dyes from the U.S. food supply and from medications. For the last 50 years, American children have increasingly been living in a toxic soup of synthetic chemicals,” he told reporters. “The FDA is also announcing plans today to authorize four additional natural color additives using natural ingredients in the coming weeks, while also accelerating the review and approval of other natural ingredient colors.”

Makary claimed studies have found a like between petroleum-based synthetic dyes and health conditions, including attention-deficit/hyperactivity disorder, obesity, diabetes, cancer and gastrointestinal issues.

‘Why are we taking a gamble?” he said. “While America’s children are sick and suffering, 41% of children have at least have at least one health condition, and one in five are on medication. The answer is not more Ozempic, more ADHD medication and more antidepressants. There’s a role for those medications, but we have to look at underlying root causes.

HHS Secretary Robert F. Kennedy Jr. was also due to speak at the news conference.

Former President Joe Biden’s administration in January started the process to ban one artificial dye, Red No. 3, which will need to be removed from food by January 2027 and from medications by 2028 because it was shown to cause cancer in rats.

Kennedy is now seeking to remove the six other petroleum-based dyes approved by the FDA. This includes Green No. 3, Citrus Red No. 2, Red No. 40, Orange B, Yellow No. 5, Yellow No. 6, Blue No. 1 and Blue No. 2. The agency is also taking steps to revoke the authorization for two synthetic food colorings — Citrus Red No. 2 and Orange B — within the coming months.

The department is also authorizing four new natural color additives.

It is not yet clear what enforcement mechanism Kennedy will seek to implement the new changes.

The timeline to phase out synthetic dyes comes after Kennedy told food industry leaders at a meeting last month that he wanted their companies to remove artificial dyes from their products by the end of his four-year term, according to a memo describing the meeting, which was obtained by ABC News.

Kennedy’s announcement Tuesday speeds up that process — and alert companies that Kennedy intends to make good on his warning quickly.

From candy to breakfast cereal to medication, synthetic food dyes are in a wide range of products that Americans consume. Studies suggest their vibrant color makes food more appealing and could even increase appetite.

The health effects of the dyes are not fully understood, but many other countries have either banned the additives outright or required food packaging warning labels about the health risks.

All dyes have the potential to spark allergic reactions for a small minority. Several dyes have been linked to hyperactivity and behavioral problems in children or have been shown to cause cancer in mice or rats — but none have shown to cause cancer in humans.

Already, red and blue states alike have taken matters into their own hands in removing artificial food dyes from certain foods. Both West Virginia and California have passed laws to ban a handful of food dyes from school lunches, with plans to extend the ban to a broader, statewide level too.

In West Virginia, the ban on artificial dyes in school lunch will go into effect in August, making it the first state in the country to implement such restraints. In California, it will take effect in 2028.

Twenty-six other states, from Iowa to Washington and from to Texas to Vermont, are considering similar legislation around banning food dyes or other chemical additives in foods, according to a list compiled by the Environmental Working Group, an advocacy organization that focuses on chemicals and toxins.

The Office of Environmental Health Hazard Assessment within California’s Environmental Protection Agency in 2021 concluded a two-year study into seven synthetic food dyes that found associations with certain neurobehavioral outcomes in some children.

Researchers also found that the FDA’s current level of “acceptable daily intake” levels for the dyes may be too high to protect children from the potential behavioral impact, the report said.

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