Bird flu case reported in Los Angeles after state officials declare emergency
CDC and NIAID
Los Angeles County health officials reported the first human case of bird flu in the area less than a week after a statewide emergency declaration was announced.
In a statement released on Monday, the L.A. County Department of Public Health said the human case of H5 bird flu was detected in an adult who was exposed to livestock infected with the virus at a worksite.
The unnamed adult had mild symptoms, has been treated with antivirals and is recovering at home, according to the agency.
“The overall risk of H5 bird flu to the public remains low,” health officials said.
There are at least 65 confirmed human cases of bird flu nationally — with at least 36 in California, according to the CDC.
California Gov. Gavin Newsom declared a state of emergency on Dec. 18 as bird flu cases were detected in dairy cows on Southern California farms. The virus had also been previously detected in the state’s Central Valley.
“This proclamation is a targeted action to ensure government agencies have the resources and flexibility they need to respond quickly to this outbreak,” Newsom said in a statement last week.
Symptoms of bird flu in humans include eye redness or discharge, fever, cough or difficulty breathing, sore throat, muscle or body aches, diarrhea and vomiting, according to health officials.
Individuals working with infected animals, including cows, poultry or wildlife, continue to be at higher risk of exposure to the virus.
“People rarely get bird flu, but those who interact with infected livestock or wildlife have a greater risk of infection. This case reminds us to take basic precautions to prevent being exposed,” Los Angeles County health officer Muntu Davis, MD, MPH, said in the statement Monday.
“People should avoid unprotected contact with sick or dead animals including cows, poultry, and wild birds; avoid consuming raw or undercooked animal products, such as raw milk; and protect pets and backyard poultry from exposure to wild animals,” Davis added.
The health official also recommended getting the seasonal flu vaccine “which can help prevent severe seasonal flu illness and lower the risk of getting both seasonal and bird flu infections at the same time if exposed.”
Human Bird Flu Cases in the U.S. as of January 6, 2025. Image by ABC News. Data via CDC.
(NEW YORK) — In the nearly nine months since the first human case of bird flu was detected in the United States, the virus has continued to spread.
The outbreak infected hundreds of herds and millions of birds before it spread to humans. As of Jan. 6, there have been 66 human cases of bird flu reported in 10 states, according to data from the Centers for Disease Control and Prevention (CDC).
Almost all confirmed cases involve direct contact with infected cattle or infected livestock.
On Tuesday, the first death of a human bird flu patient was reported in Louisiana. The patient was over the age of 65 and had underlying medical conditions, according to health officials.
The CDC says there is currently no evidence of human-to-human transmission and the risk to the general public is low.
However, public health experts say they are worried the virus could mutate and become more transmissible, amplifying the need to ramp up testing and to stockpile vaccines.
Dr. Tony Moody, a professor of pediatrics and infectious diseases specialist at Duke University, said the fact that cases have yet to pass from human to human is “both reassuring, but not completely reassuring.”
He told ABC News, “What we’re concerned about is that, eventually, we might get a variation of this strain that could pass from person to person. That’s really what we’re going to need to see, I think, to get substantial human cases and the potential for a new pandemic strain.”
He added, “So, in terms of peering into the crystal ball for 2025…I think the concern is whether or not we’re going to see something change that will turn it into a pandemic strain that could then really be a problem,” he added.
Fears of mutation or a combination virus
One fear experts have is that the virus will continue to mutate in a way that will cause more human-to-human transmissibility. The experts say that every new human case of bird flu allows the virus an opportunity to mutate.
Recent CDC data found mutations in samples of bird flu collected from the Louisiana patient. What’s more, the mutations were not found in poultry samples collected on the patient’s property, suggesting the changes appeared after the patient became infected.
Moody said that because the virus has not yet mutated in a way to spread more easily between humans, he’s not sure if or when it will happen.
“Given the number of cows that have been infected, the number of birds that have been infected and the fact that the virus essentially mutates every time it replicates, I’m kind of surprised that the mutations that they’re talking about haven’t happened yet,” he said. “So, I actually think there’s a bigger barrier to it becoming a real problem.”
Dr. Peter Hotez, co-director of the Texas Children’s Hospital Center for Vaccine Development and dean of the National School of Tropical Medicine at Baylor College of Medicine, said he believes there is a more likely scenario of the virus becoming more transmissible: an individual getting infected with bird flu and seasonal influenza at the same time.
He said this could lead to the virus “reassorting” to produce a hybrid, or recombinant, virus that could then transmit more easily from person to person.
“Everyone’s focusing on the potential for mutation; that is a serious concern for some,” he told ABC News. “The greater probability is that there could be a reassortment, what could ignite the pandemic or an epidemic.”
The experts say there is no evidence the virus is currently heading towards an epidemic or pandemic, but there has already been one case of severe disease.
Different genotypes, or genetic makeup of the virus, means there could more severe cases.
“What we’ve seen with [bird flu] in the United States is that the particular genotype that’s associated with dairy cows has primarily caused more mild disease in people,” Dr. Meghan Davis, an associate professor of environmental health and engineering at Johns Hopkins Bloomberg School of Public Health, told ABC News.
“What we’ve seen with the case in Louisiana … is caused by a different genotype, one that has been circulating in the wild birds, and these are much more severe cases,” she continued. “This highlights the ability of avian influenzas to cause a wide variety of disease … and I think it is possible that we’re going to see that moving forward.”
Making testing more available
The U.S. has begun ramping up testing with the U.S. Department of Agriculture issuing a federal order for raw milk samples nationwide to be collected and tested and the Food and Drug Administration announcing it is collecting samples of aged raw cow’s milk cheese to be tested.
However, for 2025, Hotez said he believes testing needs to be made more readily available to physicians, especially during flu season.
He said there are likely cases of bird flu going undiagnosed, and testing made more available in health care settings would catch those flying under the radar.
“I think one of the problems that we have, especially as we move into influenza season, there’s the risk that, if you’re a physician, if they want to do influenza testing, they’re only really testing for the usual seasonal influenza, they’re not testing for [bird flu],” he said. “Otherwise, we’re never going to fully know the actual extent of the problem.”
Stockpiling bird flu vaccines
In early July, the U.S. government awarded Moderna $176 million to develop and test a bird flu vaccine using mRNA technology, which is the same technology used for the COVID vaccine.
In October, federal health officials announced they were providing $72 million to vaccine manufacturers to help ensure currently available bird flu vaccines are ready to use, if needed.
There are currently no recommendations for anyone in the U.S. to be vaccinated against bird flu, but experts say that could change if the virus becomes more transmissible.
Moody said clinical trials for new vaccines are being conducted and there are already bird flu vaccines in a stockpile maintained by the U.S. government that have previously been licensed by the FDA.
However, these three vaccines were formulated to protect against older strains of bird flu so there are questions about their protectiveness.
“One of the difficulties in making a stockpile is you’re trying to predict the future. Picking which influenza is going to be a problem is always the difficult bit,” Moody said. “So, I think that those vaccines that are in the stockpile, based on the data that I’ve seen, have a pretty good chance of being helpful. Whether or not they’ll be the answer that’s a that’s a tougher question to address.”
He said the U.S. is in a better position currently to address bird flu if it becomes an epidemic or pandemic than the country was to address COVID in 2020.
“We know how to do this. We know how to make these vaccines. We know how to get everything rolled out, and so I think we are in a better position today,” Moody said.
(NEW YORK) — Outpatient health care visits for flu illnesses are at their highest levels in 15 years, according to data updated Friday by the Centers for Disease Control and Prevention.
Nearly 8% of outpatient health care visits for respiratory illnesses are due to flu-like illness, which is the highest seen since the 2009-10 flu season, during the swine flu pandemic, data shows.
During the week ending Feb. 1, 8% of emergency department visits were due to flu compared with 3.2% the same time last year, according to the CDC data.
Additionally, 31.6% of tests came back positive for flu during the week ending Feb. 1 compared to a peak of 18.2% last season, CDC data shows.
“Given the sharp rise [of flu illnesses] particularly among young children and in key regions like New York City, this is a stark reminder of how unpredictable flu seasons can be,” said Dr. John Brownstein, an epidemiologist and chief innovation officer at Boston Children’s Hospital and an ABC News contributor.
“With [influenza-like illness] rates exceeding 10% in several states and hospitalization rates climbing in older adults, this wave could put significant pressure on our health systems in the coming weeks,” he added.
What’s more, the rate of people dying from flu is now equal to the rate of people dying from COVID-19, likely for the first time since the COVID pandemic began.
The CDC estimates there have been at least 24 million illnesses, 310,000 hospitalizations and 13,000 deaths from flu so far this season.
At least 57 pediatric flu deaths have been reported so far this season, with 10 reported during the week ending Feb. 1.
Flu vaccines are available for both children and adults, but vaccination coverage remains low, meaning “many children and adults lack protection from respiratory virus infections provided by vaccines,” according to the CDC.
Data shows only 45% of adults aged 18 and older have been vaccinated against flu this season as have 45.7% of children.
CDC data also shows that overall respiratory illness activity is listed as “very high” nationwide. Currently, 12 states are listed as “very high” and 19 states are listed as “high.”
By comparison, seven states were listed as “very high” and 20 states were listed as “high” last week.
Although COVID-19 activity is “elevated” in many areas of the U.S., CDC data shows emergency department visits are at low levels and the number of laboratory tests coming back positive is falling.
Respiratory syncytial virus activity was also described as “elevated” but declining in most areas of the U.S., according to the CDC.
(NEW YORK) — Flu activity remains “elevated” in the United States but is starting to show signs of abating, according to new federal data published Friday.
The 2024-25 flu season was classified by the Centers for Disease Control and Prevention (CDC) as a “high” severity season overall and for all age groups, making it the first high severity season since 2017-2018.
During the week ending Feb. 15, 6.8% of visits to doctors’ offices were for flu-like illness, down from 7.7% of visits over the previous two weeks, CDC data shows.
Emergency department visits for flu also fell to 6.4% during the week ending Feb. 15 from more than 8% for the two weeks prior.
Additionally, 26.9% of tests came back positive for flu during the week ending Feb. 15. This is higher than the peak of 18.2% last flu season but lower than the 31.4% recorded over the previous two weeks.
The CDC estimates there have been at least 33 million illnesses, 430,000 hospitalizations and 19,000 deaths from flu so far this season
At least 86 pediatric flu deaths have been recorded so far, with 18 reported the week ending Feb. 15.
It comes as overall respiratory illness activity is listed as “high” nationwide, CDC data shows.
As of Friday, nine states are listed as having “very high” levels of respiratory virus activity and 14 states are listed as “high.” The remaining states are listed as having “moderate” or “low” levels.
Comparatively, 12 states were listed as “very high” and 20 states were listed as “high” last week.
Meanwhile, although COVID-19 activity is “elevated” in many areas of the U.S., CDC data shows emergency department visits are at low levels and the number of laboratory tests coming back positive is stable.
Respiratory syncytial virus activity was also described as “elevated” but declining in most areas of the U.S., according to the CDC.
Public health experts have recommended children and adults receive the flu and COVID vaccine as well as older adults receive the RSV vaccine, but coverage is “low,” according to the CDC.
As of Feb 8, only 45.3% of adults were vaccinated against the flu and 23,1% were vaccinated with the updated 2024-25 COVID-19 vaccine. Additionally, just 46.7% of adults ages 75 and older have received the RSV vaccine, according to CDC data.
Nearly half of all children are vaccinated against the flu at 45.8%, but just 12.1% have received the updated COVID-19 vaccine.
