WHO declares mpox a public health emergency as newer strain spreads in Africa
(NEW YORK) — The World Health Organization (WHO) declared mpox to be a public health emergency of international concern (PHEIC) on Wednesday
“Today, the Emergency Committee met and advised me that in its view, the situation constitutes a public health emergency of international concern. I have accepted that advice,” said WHO Director-General Dr. Tedros Adhanom Ghebreyesus during a media briefing on Wednesday.
In the U.S, there have been 1,634 cases of mpox reported so far this year, according to data from the U.S. Centers for Disease Control and Prevention (CDC).
That’s more than double the number of national cases seen at the same time last year but significantly lower than those seen during a U.S. mpox outbreak in 2022, CDC data shows.
PHEICs were most recently declared for the COVID-19 pandemic and the previous mpox outbreak of 2022.
Although mpox is endemic to parts of Central and Western Africa, cases have been rising dramatically in the Democratic Republic of the Congo (DRC).
This year, there have already been more than 14,000 mpox cases and 524 deaths reported in the DRC, according to the WHO.
There are two types of mpox: clade I and clade II, with clade roughly meaning they are descended from a common ancestor organism. While clade I has caused small, localized outbreaks in the DRC for years, researchers identified a clade I variant, known as clade Ib, that seems to spread mainly through sexual contact and appears to be behind the outbreak in the DRC.
Tedros said the detection of clade Ib in neighboring African countries that have never reported mpox cases before – including Burundi, Kenya, Rwanda and Uganda – led him to convene a meeting of the WHO’s emergency committee.
“The detection and rapid spread of a new clade of mpox in eastern DRC, its detection in neighboring countries that had not previously reported mpox, and the potential for further spread within Africa and beyond is very worrying,” Tedros said during the briefing.
On Monday, the Africa Centres for Disease Control and Prevention (Africa CDC) – the continent’s top health agency – declared mpox a public health emergency of continental security (PHECS) – the first such declaration since the Africa CDC’s inception in 2017, according to the agency.
On the same day, the WHO published a report that found there were a total of 934 new laboratory confirmed cases of mpox and four deaths from 26 countries in the month of June, “illustrating continuing transmission of mpox across the world.”
There have been no cases of clade I mpox reported outside Central and Eastern Africa at this time, including in the U.S., according to the CDC. The risk of the type of mpox circulating in the DRC is low to the American public, according to the CDC.
Currently, the JYNNEOS vaccine, a two-dose vaccine approved by the Food and Drug Administration to prevent smallpox and mpox, is the only vaccine being used in the U.S. to prevent mpox. Data from Africa has shown two doses of JYNNEOS are at least 85% effective in preventing mpox infection.
(NEW YORK) — As mosquito season continues, public health officials in the U.S. have been tracking several different illnesses caused by the pesky flying insect.
Health officials are reporting at least eighteen deaths from West Nile virus in the U.S. this year, with three recent deaths recorded in Wisconsin and Illinois. There have been six cases of eastern equine encephalitis (EEE), including one person who died after testing positive for the virus, as well as dengue cases recorded in several states. The viruses that cause all three illnesses are transmitted to humans via mosquito bite.
“What we’ve seen is a rapid uptake in certain viruses that haven’t been in the limelight in recent years. Both West Nile virus and ‘triple E,’ which is eastern equine encephalitis, have had an uptick, particularly post-COVID,” Dr. Larry Han, an assistant professor of public health and health sciences at Northeastern University in Boston, told ABC News.
“There’s also been a rise in dengue relative to what we’ve seen in recent years. And so, these ‘triple threats,’ you might say, have led to more attention and more worry among the general populace.”
Experts who spoke with ABC News said some of the uptick is due to the “randomness” regarding which seasons have a greater number of cases than others, coupled with the general rise in mosquito-borne viruses during the summer and early fall months.
Here are some ways to tell the difference between West Nile, EEE, and dengue. However, if you’re concerned you might have contracted any of these viruses, you should contact your doctor immediately.
How common are West Nile, EEE and dengue?
West Nile virus is the leading cause of mosquito-borne disease in the contiguous United States, according to the Centers for Disease Control and Prevention (CDC). It was first identified in the Western Hemisphere in August 1999 after people were diagnosed in New York City.
Dengue viruses are spread through bites from infected Aedes species mosquitoes, mostly found in tropical and subtropical regions of the world, according to the CDC. These mosquitoes are also responsible for spreading Zika and chikungunya viruses.
“It would be very rare to see dengue cases unless you lived in more tropical climates, so you might see this in Florida, some Southern states along the East Coast, but, for example, you would nearly never see this in Massachusetts or in the Midwest or West,” Han said.
Comparatively, EEE is quite rare, with only a few cases reported in the U.S. every year. However, similar to dengue, most cases occur in the Eastern or Gulf Coast states, according to the CDC.
What are the symptoms?
The majority of people with West Nile virus do not present with symptoms, but about one in five will experience fever along with headaches, body aches, joint pain, diarrhea, vomiting, or a rash. Symptoms typically disappear in a week or less for most people but weakness and fatigue may last for weeks or months. For some people, however, the disease can progress to something far more concerning.
“About one out of 150 of those people that develop signs and symptoms can actually develop a more severe disease, like West Nile encephalitis, where we have the swelling of the brain that could potentially be fatal,” Dr. Thomas Duszynski, director of epidemiology education at the Indiana University Richard M. Fairbanks School of Public Health, told ABC News.
Similarly, about one in four people who contract dengue develop symptoms lasting two to seven days, but symptoms are usually mild and may include fever, rash, nausea, vomiting, muscle pain, joint pain and bone pain.
Duszynski explained that most U.S. dengue cases are typically seen among people who contract it while traveling abroad, where dengue is endemic or where cases are more common, and who then bring the virus back to the U.S. Because dengue’s symptoms are not specific to the virus, they’re often confused with other illnesses, according to the CDC.
Most people who are infected with EEE show either mild symptoms or no symptoms at all, according to the CDC. However, severe cases typically present with fever, headache, chills and vomiting.
Like West Nile virus, EEE also can progress to a more severe condition, like encephalitis or meningitis, the latter of which is swelling of the membranes that surround the brain and spinal cord. Many survivors can experience ongoing neurologic problems, including convulsions, paralysis and intellectual disability. About 30% of encephalitis cases caused by EEE result in death.
“I think the mortality risk if one were to contract dengue or West Nile virus would be very low. For EEE, it’s the opposite; it’s very high,” Han said.
Treatments and vaccines
There are no disease-specific treatments for any of the viruses. The CDC recommends rest, fluids, and over-the-counter medications to relieve symptoms. Patients with severe illness often need to be hospitalized and receive additional supportive treatments, such as intravenous fluids.
There also are no vaccines available for West Nile or EEE. However, a dengue vaccine is available in the U.S. and is FDA approved for children between ages 9 and 16 who have a laboratory-confirmed previous dengue virus infection and who live in areas where dengue is endemic.
The vaccine also is available in Puerto Rico and is part of the territory’s routine childhood immunization schedule, the CDC said.
Dengue can be caused by dengue virus strains 1, 2, 3 or 4, with a person being infected multiple times over the course of their life, Duszynski told ABC News, so a vaccine may be able to help prevent infection from a different strain.
“If I got infected with one strain, if I get bit by this mosquito with the same strain, I’m probably going to be okay,’ he said. “But it’s those three other strains that are out there that … I could get infected with even though I had strain 1.”
How to best protect yourself from infection
There are no differences when it comes to protecting yourself from dengue, EEE or West Nile virus, the experts told ABC News. Prevention methods include using effective mosquito repellents, wearing long-sleeve shirts and long pants when outside, and staying in places with air conditioning, when possible. The CDC also recommends emptying containers of still or stagnant water, to eliminate places where mosquitos can breed.
“The single deadliest [animal] to the human species has been the mosquito,” Han said. “So, while we might think of sharks or we might think of lions or tigers, it’s really the mosquito that has led to the devastation of the human population multiple times throughout history.”
“I’m not saying that we should kill off all mosquitoes, because they play an important role in ecology, but there are various new techniques and strategies people are thinking about to combat mosquito-borne viruses and illnesses,” Han continued. “I’m hopeful that we can make mosquito borne viruses less of a threat to humanity.”
(NEW YORK) — A New Hampshire resident died after being infected with a rare mosquito-borne disease, health officials said Tuesday.
The resident, an adult from Hempstead — near the southeastern border with Massachusetts — had tested positive for Eastern Equine Encephalitis virus (EEEV). The patient was hospitalized due to severe central nervous system disease and died of their illness, according to an update from the state’s Department of Health & Human Services (DHHS).
This is the first reported human case of EEEV in New Hampshire in a decade after three people contracted the disease in 2014, two of whom died, DHHS said.
It’s unclear when the resident, who recently passed away, first became infected with EEEV. No other details were available including name, age or sex.
In addition to the person infected with EEEV, the virus has also been found in one horse and seven mosquito batches in New Hampshire so far this summer, according to the health department.
Neighboring states have been experiencing similar threats. In Massachusetts, 10 communities were designated as being under high or critical risk of the virus, according to the state’s Department of Public Health. Many of the areas began implementing targeted mosquito spraying to protect residents.
“In New Hampshire, mosquitos transmit infections including Eastern Equine Encephalitis Virus, West Nile Virus, and Jamestown Canyon Virus,” Dr. Benjamin Chan, New Hampshire’s state epidemiologist, said in a statement.
“We believe there is an elevated risk for EEEV infections this year in New England given the positive mosquito samples identified. The risk will continue into the fall until there is a hard frost that kills the mosquitos. Everybody should take steps to prevent mosquito bites when they are outdoors,” the statement continued.
EEEV is a rare but serious disease that spreads by bites from infected mosquitoes. It does not spread via touching or droplets from coughing or sneezing, according to the Centers for Disease Control and Prevention (CDC).
Most people who are infected either show mild symptoms or no symptoms at all. However, severe cases usually begin with fever, headache, chills and vomiting before progressing to encephalitis, which is swelling of the brain, or meningitis, which is swelling of the membranes that surround the brain and spinal cord.
Many survivors have ongoing neurologic problems including convulsions, paralysis and intellectual disability, and about 30% of encephalitis cases from this virus result in death.
There are no human vaccines and no treatments specifically for EEEV. The CDC says rest, fluids and over-the-counter pain medications may help relieve some symptoms.
As of Tuesday, four cases have been reported aside from the New Hampshire case — with one case each in Massachusetts, New Jersey, Vermont and Wisconsin, according to the CDC.
The New Hampshire DHHS said residents can protect themselves by using effective mosquito repellents, wearing long-sleeve shirts and long pants when outside and avoiding outdoor activities when mosquitoes are the most active, including early in the morning and during evening hours.
Additionally, residents are advised to remove standing water from around their homes, which attracts mosquitoes, and to make sure doors and windows have tight-fitting screens.
(HOUSTON) — A family in Texas has welcomed home all four of their rare identical quadruplets after the infants spent over three months in the neonatal intensive care unit (NICU).
The sisters — named Hannah Grace, Lucy Marie, Rebecca Claire and Petra Anne — were born on May 1, after their mom, Mercedes Sandhu, delivered them at 29 weeks and three days.
Sandhu carried what is known as a monochorionic pregnancy, meaning all four babies shared the same placenta, according to Texas Children’s Hospital, where Sandhu gave birth.
The babies were born just before Mother’s Day, but Sandhu did not have all four daughters at home until Thursday, when Rebecca was discharged from the NICU.
Hannah and Petra were discharged on July 12, followed by Lucy nearly one week later.
“We’re so happy they can be together too,” the babies’ father, Jonathan Sandhu, told Good Morning America. “The past few weeks are the only moments they have ever been apart. Even in the NICU, they were always within a few feet of each other.”
The quadruplets’ reunion at home was also the first time all four sisters got to meet their older brothers, Luke, 4, and Aaron, nearly 2, who were not allowed in the NICU because of their ages, according to Jonathan Sandhu.
“The best part has been watching our boys welcome their baby sisters … They are obsessed with the girls,” he said. “Seeing our little family come together has been the most heartwarming moment of our lives.”
The quadruplets’ birth on May 1, meant the Sandhus had welcomed six kids in a span of four years. The quadruplets were conceived naturally, without the help of fertility treatments.
When it comes to being able to differentiate the quadruplets, Jonathan Sandhu said they are able to tell two of the babies apart because they were born with hemangiomas, a benign growth of extra blood cells in the skin that is one of the most common skin conditions among infants, according to Texas Children’s Hospital.
The couple also keeps the babies in labeled bassinets and lines them up in birth order — Hannah, Lucy, Rebecca, Petra, for feedings.
“Because they’re identical, they literally have the exact same DNA so keeping them correctly identified is pretty important,” Jonathan Sandhu told GMA.
The Sandhus have been documenting the journey of their “miracle” babies on their Instagram account, @thesandhucrew.
They said the babies are proving to be healthy and happy at home, with no ongoing medical needs after their time in the NICU.
“With high order multiples, all sharing one placenta, they were at elevated risks for nearly all the bad things that can accompany premature infants,” Jonathan Sandhu said. “We’ve had a few little bumps, but nothing that ever became life-threatening or would need life-long care.”
Jonathan Sandhu said he and his wife are dealing with the normal challenges that accompany a newborn — like sleep deprivation — but multiplied by four.
“If you’ve ever taken care of a newborn at night, imagine that, but with a few more crying mouths and dirty diapers,” he explained. “My wife and I take shifts at night and one person feeding and changing multiple babies can take two hours. Then you have to repeat it all a few hours later.”